Evidence map›Paper›PMID 17024487›Full record

ArticleEuropean journal of clinical pharmacology2006

Factor analysis improves the selection of prescribing indicators.

Hanne Marie Skyggedal Rasmussen, Jens Søndergaard, Ineta Sokolowski, Jens Peter Kampmann, Morten Andersen

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Article in European journal of clinical pharmacology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Development and validation of a new Prescription Quality Index.British journal of clinical pharmacology · 2010
    Article
  3. Observational
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hanne Marie Skyggedal RasmussenResearch Unit for General Practice, Institute of Public Health, University of Southern Denmark, Odense, J.B. Winsløws Vej 9A, DK-5000, Odense, Denmark.
Jens Søndergaard
Ineta Sokolowski
Jens Peter Kampmann
Morten Andersen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo test a method for improving the selection of indicators of general practitioners' prescribing.

methodsWe conducted a prescription database study including all 180 general practices in the County of Funen, Denmark, approximately 472,000 inhabitants. Principal factor analysis was used to model correlation between 19 register-based indicators for the quality of non-steroidal anti-inflammatory drug (NSAID) prescribing.

resultsThe correlation between indicators ranged widely from 0 to 0.93. Factor analysis revealed three dimensions of quality: (1) "Coxib preference", comprising indicators directly quantifying choice of coxibs, indicators measuring expenditure per Defined Daily Dose, and indicators taking risk aspects into account, (2) "Frequent NSAID prescribing", comprising indicators quantifying prevalence or amount of NSAID prescribing, and (3) "Diverse NSAID choice", comprising indicators focusing on the width of GPs' formularies. The number of indicators for measuring the important aspects of quality in prescribing of NSAIDs could be reduced substantially by selecting the indicator in each dimension with the highest factor loading. A high preference for coxibs indicated both appropriate and inappropriate prescribing, as revealed by the correlation of the indicators in the first factor.

conclusionCorrelation and factor analysis is a feasible method that assists the selection of indicators and gives better insight into prescribing patterns.

Indexed as

Practice Patterns, Physicians'Anti-Inflammatory Agents, Non-SteroidalDatabases, FactualDenmarkDrug PrescriptionsEvidence-Based MedicineFactor Analysis, StatisticalFamily PracticeHumansPharmacoepidemiologyAnti-Inflammatory Agents, Non-Steroidal

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