ArticleApplied and environmental microbiology2006
Photolyase confers resistance to UV light but does not contribute to the symbiotic benefit of bioluminescence in Vibrio fischeri ES114.
Article in Applied and environmental microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Adapting to UV: Integrative Genomic and Structural Analysis in Bacteria from Chilean Extreme Environments.International journal of molecular sciences · 2025Article
- Diversity and evolution of bacterial bioluminescence genes in the global ocean.NAR genomics and bioinformatics · 2020Article
- The Marine Bacterium Shewanella woodyi Produces CMicrobial ecology · 2020Article
- Rethinking the roles of CRP, cAMP, and sugar-mediated global regulation in the Vibrionaceae.Current genetics · 2016Review
- Bacterial bioluminescence as a lure for marine zooplankton and fish.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Effects of luxCDABEG induction in Vibrio fischeri: enhancement of symbiotic colonization and conditional attenuation of growth in culture.Archives of microbiology · 2008Article
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Authors and funding
3 authors.
Funding
Abstract
Recent reports suggest that the selective advantage of bioluminescence for bacteria is mediated by light-dependent stimulation of photolyase to repair DNA lesions. Despite evidence for this model, photolyase mutants have not been characterized in a naturally bioluminescent bacterium, nor has this hypothesis been tested in bioluminescent bacteria under natural conditions. We have now characterized the photolyase encoded by phr in the bioluminescent bacterium Vibrio fischeri ES114. Consistent with Phr possessing photolyase activity, phr conferred light-dependent resistance to UV light. However, upon comparing ES114 to a phr mutant and a dark Delta luxCDABEG mutant, we found that bioluminescence did not detectably affect photolyase-mediated resistance to UV light. Addition of the light-stimulating autoinducer N-3-oxo-hexanoyl homoserine lactone appeared to increase UV resistance, but this was independent of photolyase or bioluminescence. Moreover, although bioluminescence confers an advantage for V. fischeri during colonization of its natural host, Euprymna scolopes, the phr mutant colonized this host to the same level as the wild type. Taken together, our results indicate that at least in V. fischeri strain ES114, the benefits of bioluminescence during symbiotic colonization are not mediated by photolyase, and although some UV resistance mechanism may be coregulated with bioluminescence, we found no evidence that light production benefits cells by stimulating photolyase in this strain.
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