Evidence map›Paper›PMID 17021056›Full record

ArticleJournal of clinical microbiology2006

Combined hepatitis C virus (HCV) antigen-antibody detection assay does not improve diagnosis for seronegative individuals with occult HCV infection.

Juan A Quiroga, Inmaculada Castillo, Margarita Pardo, Elena Rodríguez-Iñigo, Vicente Carreño

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Occult HCV Infection: The Current State of Knowledge.Iranian Red Crescent medical journal · 2015
    Review
  3. A New Twist to a Chronic HCV Infection: Occult Hepatitis C.Gastroenterology research and practice · 2015
    Review
  4. New perspectives in occult hepatitis C virus infection.World journal of gastroenterology · 2012
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Juan A QuirogaFundación para el Estudio de las Hepatitis Virales, Guzmán el Bueno 72, 28015 Madrid, Spain.
Inmaculada Castillo
Margarita Pardo
Elena Rodríguez-Iñigo
Vicente Carreño
Fundación para el Estudio de las Hepatitis Virales · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A combined hepatitis C virus (HCV) antigen-antibody assay was evaluated for 115 seronegative individuals with occult HCV infection. The assay was reactive in one patient and negative to weakly reactive in three others (all four gave indeterminate results by supplemental assay) but failed to detect HCV in the remaining patients. Despite increased sensitivity the combined assay does not improve serodiagnosis of occult HCV infection.

Indexed as

HepacivirusHepatitis CHepatitis C AntibodiesHepatitis C AntigensHumansSensitivity and SpecificityHepatitis C AntibodiesHepatitis C Antigens

Identifiers

PMID17021056
PMCPMC1698377
OpenAlexW2165446425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.