ArticleIntensive care medicine2006
Prognosis and risk factors of early onset pneumonia in ventilated patients with Guillain-Barré syndrome.
Article in Intensive care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- The neutrophil-to-lymphocyte ratio as a prognostic biomarker in Guillain-Barre syndrome: a systematic review with meta-analysis.Frontiers in neurology · 2023Pooled it
- Clinical profile and predictors of guillain-barre syndrome associated pneumonia: a retrospective cohort study.BMC neurology · 2026Article
- Article
- Critical insights for intensivists on Guillain-Barré syndrome.Annals of intensive care · 2025Review
- Characteristics and outcomes of patients with Guillain-Barré syndrome who were admitted to the intensive care unit: a retrospective observational study.The Journal of international medical research · 2024Observational
- Respiratory issues and current management in neuromuscular diseases: a narrative review.Journal of thoracic disease · 2024Review
- A retrospective analysis of the clinical profile and factors associated with mortality and poor hospital outcomes in adult Guillain-Barre syndrome patients.Scientific reports · 2024Article
- International Validation of the Erasmus Guillain-Barré Syndrome Respiratory Insufficiency Score.Annals of neurology · 2022Article
- Predicting Mechanical Ventilation Using the EGRIS in Guillain-Barré Syndrome in a Latin American Country.Neurocritical care · 2021Article
- Risk factors for the severity of Guillain-Barré syndrome and predictors of short-term prognosis of severe Guillain-Barré syndrome.Scientific reports · 2021Article
- Effect of Early Tracheostomy on Mortality of Mechanically Ventilated Patients with Guillain-Barré Syndrome: A Nationwide Observational Study.Neurocritical care · 2020Observational
- Early mechanical ventilation in patients with Guillain-Barré syndrome at high risk of respiratory failure: a randomized trial.Annals of intensive care · 2020Article
- Comparative Outcomes of Respiratory Failure Associated with Common Neuromuscular Emergencies: Myasthenia Gravis versus Guillain-Barré Syndrome.Medicina (Kaunas, Lithuania) · 2019Article
- Electrophysiological Subtypes and Prognostic Factors of Guillain-Barre Syndrome in Northern China.Frontiers in neurology · 2019Article
- Swallowing and swallowing-breathing interaction as predictors of intubation in Guillain-Barré syndrome.Brain and behavior · 2017Article
- Comparison of suction above cuff and standard endotracheal tubes in neurological patients for the incidence of ventilator-associated pneumonia and in-hospital outcome: A randomized controlled pilot study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016Article
- Predictors for mechanical ventilation and short-term prognosis in patients with Guillain-Barré syndrome.Critical care (London, England) · 2015Article
- Relevance of anxiety in clinical practice of Guillain-Barre syndrome: a cohort study.BMJ open · 2012Article
- Selective digestive tract decontamination decreases time on ventilator in Guillain-Barré syndrome.Neurocritical care · 2011Article
- A simple functional marker to predict the need for prolonged mechanical ventilation in patients with Guillain-Barré syndrome.Critical care (London, England) · 2011Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInvasive mechanical ventilation is required in 30% of patients with Guillain-Barré syndrome (GBS) and is associated with pneumonia and increased mortality. Our objective was to determine the incidence, characteristics, outcomes, and risk factors of pneumonia in GBS patients receiving mechanical ventilation. DESIGN AND
settingStudy of a prospective database in an intensive care unit of a university hospital. PATIENTS: The study included 81 patients who required intubation for GBS. Neurological findings, vital capacity, and signs of respiratory distress were recorded at admission and at intubation. A score predicting the risk of intubation (0-4) was calculated for each patient. Pneumonia was diagnosed based on predefined criteria and retrospectively confirmed by two observers. Early-onset pneumonia was defined as pneumonia diagnosed within 5 days after intubation. MEASUREMENTS AND
resultsMean vital capacity was 57 +/- 22% of predicted at admission and 33 +/- 11% at intubation. Pneumonia developed in 63 patients (78%), including 48 with early-onset pneumonia. Bacteria were consistent with aspiration. Of the 63 patients with pneumonia 11 (18%) had septic shock, 6 (10%) had acute respiratory distress syndrome, and 9 (14%) died. In the univariate analysis milder weakness, a lower risk of intubation (score < 2), and time from admission to intubation longer than 2 days were associated with early-onset pneumonia. Time from admission to intubation was the only independent predictor in the multivariate logistic regression model.
conclusionsEarly-onset pneumonia is a common and severe complication that is related to aspiration in patients with GBS. Delaying intubation may increase the risk of early-onset pneumonia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.