ArticleAmerican journal of public health2006
Ashkenazi Jews and breast cancer: the consequences of linking ethnic identity to genetic disease.
Article in American journal of public health, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 42 citations in OpenAlex.
- A proposal for an inclusive working definition of genetic discrimination to promote a more coherent debate.Nature genetics · 2024Review
- A scalable, aggregated genotypic-phenotypic database for human disease variation.Database : the journal of biological databases and curation · 2019Article
- Genetics in an isolated population like Finland: a different basis for genomic medicine?Journal of community genetics · 2017Article
- Survey on Addressing the Information and Support Needs of Jewish Women at Increased Risk for or Diagnosed with Breast Cancer: The Sharsheret Experience.Healthcare (Basel, Switzerland) · 2015Article
- Phase changes in the BRCA policy domain.Journal of religion and health · 2014Review
- The influence of health care policies and health care system distrust on willingness to undergo genetic testing.Medical care · 2012Article
- Admixture mapping: from paradigms of race and ethnicity to population history.The HUGO journal · 2010Article
- A new conceptualization of ethnicity for social epidemiologic and health equity research.Social science & medicine (1982) · 2010Article
- Recent advances of genetic ancestry testing in biomedical research and direct to consumer testing.Clinical genetics · 2009Review
- Race and ancestry in biomedical research: exploring the challenges.Genome medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We explored the advantages and disadvantages of using ethnic categories in genetic research. With the discovery that certain breast cancer gene mutations appeared to be more prevalent in Ashkenazi Jews, breast cancer researchers moved their focus from high-risk families to ethnicity. The concept of Ashkenazi Jews as genetically unique, a legacy of Tay-Sachs disease research and a particular reading of history, shaped this new approach even as methodological imprecision and new genetic and historical research challenged it. Our findings cast doubt on the accuracy and desirability of linking ethnic groups to genetic disease. Such linkages exaggerate genetic differences among ethnic groups and lead to unequal access to testing and therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.