Evidence map›Paper›PMID 17016553›Full record

ArticleThe Journal of clinical investigation2006

Imaging tumor angiogenesis.

Kristy Red-Horse, Napoleone Ferrara

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of clinical investigation, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. A method for assessing the microvasculature in a murine tumor model using contrast-enhanced ultrasonography.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2008
    Article
  6. Therapeutic angiogenesis for brain ischemia: a brief review.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2007
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kristy Red-HorseGenentech Inc., South San Francisco, California 94080, USA.
Napoleone Ferrara

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the discovery of vascular-specific growth factors with angiogenic activity, there has been a significant effort to develop cancer drugs that restrict tumorigenesis by targeting the blood supply. In this issue of the JCI, Mancuso et al. use mouse models to better understand the plasticity of the tumor vasculature in the face of antiangiogenic therapy (see the related article beginning on page 2610). They describe a rapid regrowth of the tumor vasculature following withdrawal of VEGFR inhibitors, emphasizing the importance of fully understanding the function of these and similar treatments used in the clinic at the cellular and molecular level.

Indexed as

Angiogenesis InhibitorsAnimalsBasement MembraneEndothelium, VascularMiceNeoplasmsNeovascularization, PathologicPlatelet Endothelial Cell Adhesion Molecule-1Receptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AAngiogenesis InhibitorsPlatelet Endothelial Cell Adhesion Molecule-1Receptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor Avascular endothelial growth factor A, mouse

Identifiers

PMID17016553
PMCPMC1578634
OpenAlexW2067137229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.