ArticleProceedings. Biological sciences2006
Genetic models of homosexuality: generating testable predictions.
Article in Proceedings. Biological sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Sexual antagonism, mating systems, and recombination suppression on sex chromosomes.Evolution letters · 2026Article
- Rethinking same-sex sexual behavior: From sensory error to social function.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The Evolution of Same-sex Sexual Behavior: Using Old Theory to Answer New Questions.Integrative and comparative biology · 2026Review
- Explaining sex: contrast between social and sexual selection.Biology of sex differences · 2025Review
- The maintenance of genetic polymorphism underlying sexually antagonistic traits.Evolution letters · 2025Article
- Biological, genetic, neurological and environmental influences on homosexuality-a narrative review.Frontiers in behavioral neuroscience · 2025Review
- Biological constraint, evolutionary spandrels and antagonistic pleiotropy.Ageing research reviews · 2024Review
- Same-sex sexual behaviour among mammals is widely observed, yet seldomly reported: Evidence from an online expert survey.PloS one · 2024Article
- Male androphilia, fraternal birth order, and female fecundity in Samoa: A 10-y retrospective.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Same-sex sociosexual behaviour is widespread and heritable in male rhesus macaques.Nature ecology & evolution · 2023Article
- Genomic evidence consistent with antagonistic pleiotropy may help explain the evolutionary maintenance of same-sex sexual behaviour in humans.Nature human behaviour · 2021Article
- Same-sex sexual behaviour and selection for indiscriminate mating.Nature ecology & evolution · 2021Article
- Sexual Attraction to Both Genders in Ambiphilic Men: Evidence from Implicit Cognitions.Archives of sexual behavior · 2020Article
- Antagonistic Pleiotropy in Human Disease.Journal of molecular evolution · 2020Review
- An alternative hypothesis for the evolution of same-sex sexual behaviour in animals.Nature ecology & evolution · 2019Review
- Prosociality and a Sociosexual Hypothesis for the Evolution of Same-Sex Attraction in Humans.Frontiers in psychology · 2019Article
- Possible Balancing Selection in Human Female Homosexuality.Human nature (Hawthorne, N.Y.) · 2018Article
- Sexually antagonistic selection on genetic variation underlying both male and female same-sex sexual behavior.BMC evolutionary biology · 2016Article
- Rapid evolution of the intersexual genetic correlation for fitness in Drosophila melanogaster.Evolution; international journal of organic evolution · 2016Article
- A test of genetic models for the evolutionary maintenance of same-sex sexual behaviour.Proceedings. Biological sciences · 2015Article
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Authors and funding
2 authors.
Funding
Abstract
Homosexuality is a common occurrence in humans and other species, yet its genetic and evolutionary basis is poorly understood. Here, we formulate and study a series of simple mathematical models for the purpose of predicting empirical patterns that can be used to determine the form of selection that leads to polymorphism of genes influencing homosexuality. Specifically, we develop theory to make contrasting predictions about the genetic characteristics of genes influencing homosexuality including: (i) chromosomal location, (ii) dominance among segregating alleles and (iii) effect sizes that distinguish between the two major models for their polymorphism: the overdominance and sexual antagonism models. We conclude that the measurement of the genetic characteristics of quantitative trait loci (QTLs) found in genomic screens for genes influencing homosexuality can be highly informative in resolving the form of natural selection maintaining their polymorphism.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.