ArticleProceedings. Biological sciences2006
Do distantly related parasites rely on the same proximate factors to alter the behaviour of their hosts?
Article in Proceedings. Biological sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Evolution and Ecology of Host Manipulation in Helminth Parasites: A Phylogenetic Meta-Analysis.Ecology letters · 2026Pooled it
- Parasite-Induced Changes in the Nervous System of the Shore CrabInternational journal of molecular sciences · 2026Article
- Gene Expression Associated With Behaviour Manipulation in Wood Ants Infected With Larval Lancet Fluke, Dicrocoelium dendriticum.Molecular ecology · 2025Article
- The caterpillar Manduca sexta brain shows changes in gene expression and protein abundance correlating with parasitic manipulation of behaviour.Scientific reports · 2024Article
- Laser-based selective killing of a manipulative parasite reveals partial reversibility of phenotypic alterations in its intermediate host.Current research in parasitology & vector-borne diseases · 2024Article
- Parasite manipulation of host phenotypes inferred from transcriptional analyses in a trematode-amphipod system.Molecular ecology · 2023Article
- Article
- Host behaviour alteration by its parasite: from brain gene expression to functional test.Proceedings. Biological sciences · 2020Article
- A molecular war: convergent and ontogenetic evidence for adaptive host manipulation in related parasites infecting divergent hosts.Proceedings. Biological sciences · 2019Article
- Infection with Plasmodium berghei ookinetes alters protein expression in the brain of Anopheles albimanus mosquitoes.Parasites & vectors · 2016Article
- Conflicts over host manipulation between different parasites and pathogens: Investigating the ecological and medical consequences.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016Review
- Inter- and intraspecific conflicts between parasites over host manipulation.Proceedings. Biological sciences · 2016Article
- Identification of candidate mimicry proteins involved in parasite-driven phenotypic changes.Parasites & vectors · 2015Article
- Microbiomes, plausible players or not in alteration of host behavior.Frontiers in microbiology · 2014Article
- Parasitic manipulation and neuroinflammation: Evidence from the system Microphallus papillorobustus (Trematoda) - Gammarus (Crustacea).Parasites & vectors · 2010Article
Corrections and comments
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9 authors.
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Abstract
Phylogenetically unrelated parasites often increase the chances of their transmission by inducing similar phenotypic changes in their hosts. However, it is not known whether these convergent strategies rely on the same biochemical precursors. In this paper, we explored such aspects by studying two gammarid species (Gammarus insensibilis and Gammarus pulex; Crustacea: Amphipoda: Gammaridae) serving as intermediate hosts in the life cycle of two distantly related parasites: the trematode, Microphallus papillorobustus and the acanthocephalan, Polymorphus minutus. Both these parasite species are known to manipulate the behaviour of their amphipod hosts, bringing them towards the water surface, where they are preferentially eaten by aquatic birds (definitive hosts). By studying and comparing the brains of infected G. insensibilis and G. pulex with proteomics tools, we have elucidated some of the proximate causes involved in the parasite-induced alterations of host behaviour for each system. Protein identifications suggest that altered physiological compartments in hosts can be similar (e.g. immunoneural connexions) or different (e.g. vision process), and hence specific to the host-parasite association considered. Moreover, proteins required to alter the same physiological compartment can be specific or conversely common in both systems, illustrating in the latter case a molecular convergence in the proximate mechanisms of manipulation.
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