ArticleSubstance abuse treatment, prevention, and policy2006
Homeless drug users' awareness and risk perception of peer "take home naloxone" use--a qualitative study.
Article in Substance abuse treatment, prevention, and policy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- A systematic review of the distribution of take-home naloxone in low- and middle-income countries and barriers to the implementation of take-home naloxone programs.Harm reduction journal · 2022Pooled it
- Provision of peer support at the intersection of homelessness and problem substance use services: a systematic 'state of the art' review.BMC public health · 2020Pooled it
- Pooled it
- Emotional reactions of trained overdose responders who use opioids following intervention in an overdose event.Substance abuse · 2022Trial
- Factors associated with withdrawal symptoms and anger among people resuscitated from an opioid overdose by take-home naloxone: Exploratory mixed methods analysis.Journal of substance abuse treatment · 2020Trial
- Take-home emergency naloxone to prevent heroin overdose deaths after prison release: rationale and practicalities for the N-ALIVE randomized trial.Journal of urban health : bulletin of the New York Academy of Medicine · 2013Trial
- Perceptions surrounding intranasal naloxone use and access among a population experiencing homelessness.Exploratory research in clinical and social pharmacy · 2026Article
- The effects of vaped cannabis on the severity of naloxone-precipitated opioid withdrawal.Experimental and clinical psychopharmacology · 2026Article
- "I don't let anybody die on my watch": perspectives on the intersection of community overdose response and emergency medical services among people who use drugs in Seattle, WA.Harm reduction journal · 2025Article
- Patterns of socioeconomic marginalization and non-fatal overdose among people who use drugs: A gender-stratified repeated measures latent class analysis.Social science & medicine (1982) · 2025Article
- Stakeholders' Perceptions of Factors Influencing the Use of Take-Home-Naloxone.Pharmacy (Basel, Switzerland) · 2020Review
- Naloxone dosage for opioid reversal: current evidence and clinical implications.Therapeutic advances in drug safety · 2018Review
- Why are some people who have received overdose education and naloxone reticent to call Emergency Medical Services in the event of overdose?The International journal on drug policy · 2017Article
- Experts by Experience: Peer Support and its Use with the Homeless.Community mental health journal · 2017Review
- Evaluating the impact of a national naloxone programme on ambulance attendance at overdose incidents: a controlled time-series analysis.Addiction (Abingdon, England) · 2017Article
- A Review of Opioid Overdose Prevention and Naloxone Prescribing: Implications for Translating Community Programming Into Clinical Practice.Substance abuse · 2015Review
- Attitudes and knowledge about naloxone and overdose prevention among detained drug users in Ningbo, China.Substance abuse treatment, prevention, and policy · 2012Article
- 'I saved a life': a heroin addict's reflections on managing an overdose using 'take home naloxone'.BMJ case reports · 2010Article
- Attitudes of Australian heroin users to peer distribution of naloxone for heroin overdose: perspectives on intranasal administration.Journal of urban health : bulletin of the New York Academy of Medicine · 2008Article
- Endogenous opiates and behavior: 2006.Peptides · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeer use of take home naloxone has the potential to reduce drug related deaths. There appears to be a paucity of research amongst homeless drug users on the topic. This study explores the acceptability and potential risk of peer use of naloxone amongst homeless drug users. From the findings the most feasible model for future treatment provision is suggested.
methodsIn depth face-to-face interviews conducted in one primary care centre and two voluntary organisation centres providing services to homeless drug users in a large UK cosmopolitan city. Interviews recorded, transcribed and analysed thematically by framework techniques.
resultsHomeless people recognise signs of a heroin overdose and many are prepared to take responsibility to give naloxone, providing prior training and support is provided. Previous reports of the theoretical potential for abuse and malicious use may have been overplayed.
conclusionThere is insufficient evidence to recommend providing "over the counter" take home naloxone" to UK homeless injecting drug users. However a programme of peer use of take home naloxone amongst homeless drug users could be feasible providing prior training is provided. Peer education within a health promotion framework will optimise success as current professionally led health promotion initiatives are failing to have a positive impact amongst homeless drug users.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.