ArticleThe Plant cell2006
Increased level of polyploidy1, a conserved repressor of CYCLINA2 transcription, controls endoreduplication in Arabidopsis.
Article in The Plant cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 74 citations in OpenAlex.
- The potato RNA metabolism machinery is targeted by the cyst nematode effector RHA1B for successful parasitism.The Plant cell · 2024Article
- TEB/POLQ plays dual roles in protecting Arabidopsis from NO-induced DNA damage.Nucleic acids research · 2022Article
- Arabidopsis thaliana subclass I ACTIN DEPOLYMERIZING FACTORs and vegetative ACTIN2/8 are novel regulators of endoreplication.Journal of plant research · 2021Article
- Fruit size control by a zinc finger protein regulating pericarp cell size in tomato.Molecular horticulture · 2021Article
- Isolation of Lineage Specific Nuclei Based on Distinct Endoreduplication Levels and Tissue-Specific Markers to Study Chromatin Accessibility Landscapes.Plants (Basel, Switzerland) · 2020Article
- Spliceosome disassembly factors ILP1 and NTR1 promote miRNA biogenesis in Arabidopsis thaliana.Nucleic acids research · 2019Article
- SnRK1 Kinase and the NAC Transcription Factor SOG1 Are Components of a Novel Signaling Pathway Mediating the Low Energy Response Triggered by ATP Depletion.Frontiers in plant science · 2019Article
- A2-type cyclin is required for the asymmetric entry division in rice stomatal development.Journal of experimental botany · 2018Article
- Comparative metabolomics and glycolysis enzyme profiling of embryogenic and nonembryogenic grape cells.FEBS open bio · 2018Article
- Spontaneous polyploidization in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Combination ofHorticulture research · 2017Article
- Ethylene-Mediated Regulation of A2-Type CYCLINs Modulates Hyponastic Growth in Arabidopsis.Plant physiology · 2015Article
- Genome-wide association mapping of growth dynamics detects time-specific and general quantitative trait loci.Journal of experimental botany · 2015Article
- NTR1 is required for transcription elongation checkpoints at alternative exons in Arabidopsis.The EMBO journal · 2015Article
- Altered expression of Arabidopsis genes in response to a multifunctional geminivirus pathogenicity protein.BMC plant biology · 2014Article
- Discovery and characterization of two novel salt-tolerance genes in Puccinellia tenuiflora.International journal of molecular sciences · 2014Article
- Leaf development: a cellular perspective.Frontiers in plant science · 2014Review
- Article
- Control of plant trichome and root-hair development by a tomato (Solanum lycopersicum) R3 MYB transcription factor.PloS one · 2013Article
- Regulating DNA replication in plants.Cold Spring Harbor perspectives in biology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endoreduplication is a type of cell cycle in which DNA replication continues without cell division. We have isolated several dominant mutants from Arabidopsis thaliana activation tagging lines by flow cytometry. One of the mutants, increased level of polyploidy1-1D (ilp1-1D), showed increased polyploidy in both light- and dark-grown hypocotyls. The corresponding gene of ilp1-1D encodes a protein homologous to the C-terminal region of mammalian GC binding factor. We demonstrate that this protein functions as a transcriptional repressor in vivo. The expression of all members of the CYCLINA2 (CYCA2) family was reduced in an ILP1 overexpressing line, and the mouse (Mus musculus) homolog of ILP1 repressed cyclin A2 expression in mouse NIH3T3 cells. T-DNA insertion mutants of ILP1 showed reduced polyploidy and upregulated all CYCA2 expression. Furthermore, loss of CYCA2;1 expression induces an increase in polyploidy in Arabidopsis. We demonstrate that this protein regulates endoreduplication through control of CYCA2 expression in Arabidopsis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.