Evidence map›Paper›PMID 17012061›Full record

ReviewNeuroRx : the journal of the American Society for Experimental NeuroTherapeutics2006

Noninvasive brain stimulation in stroke rehabilitation.

Brian R Webster, Pablo A Celnik, Leonardo G Cohen

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03122821 nacompletednot on this mapstarted 2017, after this paper: background citation

Effect of Transcranial Stimulation Augmented With Mental Imagery in Upper Limb Stroke Rehabilitation: A Randomized Controlled Trial

TypeinterventionalSponsorMajmaah UniversityRan2017 to 2022Enrolled64ConditionsStrokeArmsReal Transcranial direct stimulation+Mental Imagery, Sham Transcranial Direct Stimulation +Mental Imagery
NCT03562663 nacompletednot on this mapstarted 2012, after this paper: background citation

Transcranial Direct Current Stimulation and Robotic Training in Chronic Stroke

TypeinterventionalSponsorBurke Medical Research InstituteRan2012 to 2016Enrolled82ConditionsChronic StrokeArmsTranscranial direct current stimulation, Upper extremity robotics
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it, 166 citations in OpenAlex.

  1. Efficacy of transcranial direct current stimulation in patients with dysphagia after stroke: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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  8. The evolution of neuromodulation for chronic stroke: From neuroplasticity mechanisms to brain-computer interfaces.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Brian R WebsterHuman Cortical Physiology Section and Stroke Neurorehabilitation Clinic, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA.
Pablo A Celnik
Leonardo G Cohen
National Institutes of Health · USNational Institute of Neurological Disorders and Stroke · US

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

Stroke is a common disorder that produces a major burden to society, largely through long-lasting motor disability in survivors. Recent studies have broadened our understanding of the processes underlying recovery of motor function after stroke. Bilateral motor regions of the brain experience substantial reorganization after stroke, including changes in the strength of interhemispheric inhibitory interactions. Our understanding of the extent to which different forms of reorganization contribute to behavioral gains in the rehabilitative process, although still limited, has led to the formulation of novel interventional strategies to regain motor function. Transcranial magnetic (TMS) and DC (tDCS) electrical stimulation are noninvasive brain stimulation techniques that modulate cortical excitability in both healthy individuals and stroke patients. These techniques can enhance the effect of training on performance of various motor tasks, including those that mimic activities of daily living. This review looks at the effects of TMS and tDCS on motor cortical function and motor performance in healthy volunteers and in patients with stroke. Both techniques can either enhance or suppress cortical excitability, and may move to the clinical arena as strategies to enhance the beneficial effects of customarily used neurorehabilitative treatments after stroke.

Indexed as

Electric Stimulation TherapyStroke RehabilitationTranscranial Magnetic StimulationAnimalsFunctional LateralityHumansStroke

Identifiers

PMID17012061
PMCPMC3593409
OpenAlexW2162257800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.