ArticleDigestive diseases and sciences2006
Role of serum tumor markers in monitoring for recurrence of gastric cancer following radical gastrectomy.
Article in Digestive diseases and sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2014Pooled it
- Article
- Analysis and Exploration of the Relationship Between the Status of Serum Tumor Markers and Clinicopathological Features and Curative Effects in Gastric Cancer and Gastroesophageal Junction Tumor.OncoTargets and therapy · 2025Article
- Exosomal LINC00853 promotes progression of gastric cancer via the MAP17/PDZK1/AKT signaling pathway.Non-coding RNA research · 2024Article
- Novel nomogram and risk stratification for peritoneal recurrence after curative resection in gastric cancer.Scientific reports · 2024Article
- Tumor biomarkers for diagnosis, prognosis and targeted therapy.Signal transduction and targeted therapy · 2024Review
- Gastric and gastroesophageal junction cancer: Risk factors and prophylactic treatments for prevention of peritoneal recurrence after curative intent surgery.Annals of gastroenterological surgery · 2022Review
- Comparison of CEA and CA19-9 as a predictive factor for recurrence after curative gastrectomy in gastric cancer.BMC surgery · 2022Review
- The prognostic value of postoperative tumor marker conversion for gastric cancer.Korean journal of clinical oncology · 2020Article
- Prognostic Value of Changes in Preoperative and Postoperative Serum CA19-9 Levels in Gastric Cancer.Frontiers in oncology · 2020Article
- Carbohydrate Antigen 19-9, Carcinoembryonic Antigen, and Carbohydrate Antigen 72-4 in Gastric Cancer: Is the Old Band Still Playing?Gastrointestinal tumors · 2018Review
- Use of serum and peritoneal CEA and CA19-9 in prediction of peritoneal dissemination and survival of gastric adenocarcinoma patients: are they prognostic factors?Annals of the Royal College of Surgeons of England · 2018Observational
- Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer?Gastroenterology research and practice · 2018Article
- Follow-up after curative resection for gastric cancer: Is it time to tailor it?World journal of gastroenterology · 2017Article
- Prognostic significance of preoperative serum CA125, CA19-9 and CEA in gastric carcinoma.Oncotarget · 2016Article
- Extremely high expression of serum alpha-fetoprotein level of gastric adenocarcinoma: a rare case with an unexpected well-prognosis.SpringerPlus · 2016Article
- The value of postoperative serum carcinoembryonic antigen and carbohydrate antigen 19-9 levels for the early detection of gastric cancer recurrence after curative resection.Journal of gastric cancer · 2014Article
- Prognostic value of preoperative serum tumor markers in gastric cancer.World journal of clinical oncology · 2014Article
- Clinical utility of tumor marker cutoff ratio and a combination scoring system of preoperative carcinoembryonic antigen, carbohydrate antigen 19-9, carbohydrate antigen 72-4 levels in gastric cancer.Journal of the Korean Surgical Society · 2013Article
- High level of preoperative carbohydrate antigen 19-9 is a poor survival predictor in gastric cancer.World journal of gastroenterology · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been suggested that the serum tumor markers AFP, CEA, and CA19-9 may serve as prognostic factors or indicators for recurrence after radical gastrectomy for gastric cancer. We compared the value of these markers in a group with (n=52) and a group without recurrent gastric cancer (n=52) according to the site of recurrence. Serum levels of tumor markers were measured at the time of preoperative diagnosis and at follow-up. At least one tumor marker was positive preoperatively in 20 with recurrence vs. 7 controls (p=0.007). The peritoneum was the most common recurrent site. The positive predictive value of AFP was high at the time of diagnosis and CA19-9 positivity was high at the time of recurrence. Positive CEA suggested recurrence to the liver. In summary, an elevated tumor marker at diagnosis or during follow up may identify patients at higher risk for a recurrence. CA19-9 may be especially useful as a marker for peritoneal recurrence of the gastric cancer, and CEA for recurrence to liver.
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