Evidence map›Paper›PMID 17007009›Full record

ReviewWorld journal of gastroenterology2006

Immune response to H. pylori.

Giovanni Suarez, Victor E Reyes, Ellen J Beswick

Open access · hybridAbstract readEditorialReview
In one paragraph

Review in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Adjuvants forVirulence · 2024
    Review
  5. The immunopathogenesis ofFrontiers in microbiology · 2024
    Review
  6. Mucosal Immunity Related to CD8Pediatric gastroenterology, hepatology & nutrition · 2024
    Article
  7. Microorganisms · 2023
    Review
  8. Review
  9. Fermented-Food science & nutrition · 2021
    Article
  10. Article
  11. Tim-3 Up-regulation in Patients with Gastric Cancer and Peptic Ulcer DiseaseAsian Pacific journal of cancer prevention : APJCP · 2017
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Giovanni Suarez
Victor E Reyes
Ellen J Beswick
The University of Texas Medical Branch at Galveston · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
Training in Emerging Infectious Diseases and BiodefenseT32AI007536 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WHITE, ARTHUR CLINTON · 1998 to 2013
$4.1M
IMPAIRED TUMOR IMMUNITY DURING H PYLORI INFECTIONR01DK050669 · NIDDK · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI REYES, VICTOR E · 1995 to 2003
$1.1M
NIAID NIH HHS T32 AI007536NIAID NIH HHS T32 AI007536-06NIDDK NIH HHS DK50669NIDDK NIH HHS DK56338NIDDK NIH HHS P30 DK056338NIDDK NIH HHS R01 DK050669
6 · The paper itself

Abstract

The gastric mucosa separates the underlying tissue from the vast array of antigens that traffic through the stomach lumen. While the extreme pH of this environment is essential in aiding the activation of enzymes and food digestion, it also renders the gastric epithelium free from bacterial colonization, with the exception of one important human pathogen, H. pylori. This bacterium has developed mechanisms to survive the harsh environment of the stomach, actively move through the mucosal layer, attach to the epithelium, evade immune responses, and achieve persistent colonization. While a hallmark of this infection is a marked inflammatory response with the infiltration of various immune cells into the infected gastric mucosa, the host immune response is unable to clear the infection and may actually contribute to the associated pathogenesis. Here, we review the host responses involved during infection with H. pylori and how they are influenced by this bacterium.

Indexed as

Antibodies, BacterialAntigens, BacterialGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansImmunity, MucosalT-LymphocytesAntibodies, BacterialAntigens, Bacterial

Identifiers

PMID17007009
PMCPMC4088157
OpenAlexW1590680103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.