ArticleSexually transmitted infections2007
Incidence and risk factors for urethral and anal gonorrhoea and chlamydia in a cohort of HIV-negative homosexual men: the Health in Men Study.
Article in Sexually transmitted infections, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.
- Pooled it
- Positive Nucleic Acid Amplification Test Results Are Rarely Indicative of a Viable Rectal Chlamydia trachomatis Infection Among Men With Anal Exposures Other Than Receptive Anal Sex.Sexually transmitted diseases · 2026Article
- Bacterial sexually transmitted infections and related antibiotic use among individuals eligible for doxycycline post-exposure prophylaxis in the United States.Nature communications · 2025Article
- Separating Infectious Proctitis from Inflammatory Bowel Disease-A Common Clinical Conundrum.Microorganisms · 2024Review
- The incubation for urethral gonorrhoea among men who have sex with men with and without oropharyngeal gonorrhoea.Epidemiology and infection · 2024Article
- Partnership types and coital frequency as predictors of gonorrhea and chlamydia among young MSM and young transgender women.International journal of STD & AIDS · 2023Article
- The Natural History of Rectal Gonococcal and Chlamydial Infections: The ExGen Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Observational
- Sexual behaviours associated with incident high-risk anal human papillomavirus among gay and bisexual men.Sexually transmitted infections · 2022Article
- Lubrication Practices and Receptive Anal Sex: Implications for STI Transmission and Prevention.Sexual medicine · 2021Article
- Modelling the multiple anatomical site transmission of Mycoplasma genitalium among men who have sex with men in Australia.Scientific reports · 2021Article
- Chlamydia trachomatis transmission between the oropharynx, urethra and anorectum in men who have sex with men: a mathematical model.BMC medicine · 2020Article
- Bacterial Load of Chlamydia trachomatis in the Posterior Oropharynx, Tonsillar Fossae, and Saliva among Men Who Have Sex with Men with Untreated Oropharyngeal Chlamydia.Journal of clinical microbiology · 2019Article
- The role of saliva in gonorrhoea and chlamydia transmission to extragenital sites among men who have sex with men: new insights into transmission.Journal of the International AIDS Society · 2019Review
- Towards an Integration of PrEP into a Safe Sex Ethics Framework for Men Who Have Sex with Men.Public health ethics · 2019Article
- A dynamic power-law sexual network model of gonorrhoea outbreaks.PLoS computational biology · 2019Article
- A Web of Complexity: Untangling the Routes of Rectal Chlamydia Acquisition.Sexually transmitted diseases · 2018Article
- Concordance of gonorrhoea of the rectum, pharynx and urethra in same-sex male partnerships attending a sexual health service in Melbourne, Australia.BMC infectious diseases · 2018Article
- Impact of Rapid Susceptibility Testing and Antibiotic Selection Strategy on the Emergence and Spread of Antibiotic Resistance in Gonorrhea.The Journal of infectious diseases · 2017Article
- Estimating the fitness cost and benefit of cefixime resistance in Neisseria gonorrhoeae to inform prescription policy: A modelling study.PLoS medicine · 2017Article
- Kiss and Tell: Limited Empirical Data on Oropharyngeal Neisseria gonorrhoeae Among Men Who Have Sex With Men and Implications for Modeling.Sexually transmitted diseases · 2017Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundEarly detection and treatment of bacterial sexually transmitted infections has been advocated as an HIV prevention strategy.
aimTo inform screening guidelines, the incidence and risk factors for urethral and anal gonorrhoea and chlamydia were studied in a prospective cohort of community-based HIV negative homosexual men in Sydney, New South Wales, Australia.
methodsAll participants were offered annual screening for gonorrhoea and chlamydia (study-visit diagnoses) on urine and anal swabs using nucleic acid amplification. Participants also reported diagnoses of gonorrhoea and chlamydia made elsewhere between interviews (interval diagnoses). All diagnoses were summed to create a combined incidence rate, and detailed data on specific sexual practices with casual and regular partners were collected.
resultsAmong 1427 men enrolled, the combined incidence rates were 3.49 and 2.96 per 100 person-years for urethral and anal gonorrhoea, respectively; and 7.43 and 4.98 per 100 person-years for urethral and anal chlamydia, respectively. Urethral infections were associated with unprotected anal intercourse (UAI) with HIV-positive partners (hazard ratio (HR) = 2.58, 95% CI 1.10 to 6.05 for urethral gonorrhoea) and with frequent insertive oral sex (p for trend 0.007 for urethral chlamydia). Anal infections were associated with receptive UAI (p for trend 0.001 for both anal gonorrhoea and chlamydia) and other receptive anal sexual practices. Stratified analyses showed the independence of the associations of insertive oral sex with urethral infections and of non-intercourse receptive anal practices with anal infections.
conclusionIncident gonorrhoea and chlamydia were common. Risk behaviours for both urethral and anal infections were not restricted to UAI. Screening that includes tests for anal and urethral infections should be considered for all sexually active homosexual men, not just for those who report UAI.
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Registered trials
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