ArticleBritish journal of sports medicine2006
Muscle-specific creatine kinase gene polymorphism and running economy responses to an 18-week 5000-m training programme.
Article in British journal of sports medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Artificial intelligence and sports genomics: advancing precision sports science and athletic performance.Frontiers in sports and active living · 2026Review
- Decoding endurance performance: integrative genomic and epigenetic insights into the molecular basis of athletic adaptation.Frontiers in systems biology · 2026Review
- Genetics and sports performance: the present and future in the identification of talent for sports based on DNA testing.European journal of applied physiology · 2022Review
- Genetic profile in genes associated with muscle injuries and injury etiology in professional soccer players.Frontiers in genetics · 2022Article
- Genetic profiles to identify talents in elite endurance athletes and professional football players.PloS one · 2022Article
- Review
- Article
- Ancestral contribution of the muscle-specific creatine kinase (CKM) polymorphism rs4884 in the knee osteoarthritis risk: a preliminary study.Clinical rheumatology · 2021Article
- Do ACE and CKMM gene variations have potent effects on physical performance in inactive male adolescents?Molecular biology reports · 2019Article
- An innovative way to highlight the power of each polymorphism on elite athletes phenotype expression.European journal of translational myology · 2018Article
- A meta-analysis of the association of CKM gene rs8111989 polymorphism with sport performance.Biology of sport · 2017Article
- Molecular Characterization and Expression Analysis of Creatine Kinase Muscle (CK-M) Gene in Horse.Asian-Australasian journal of animal sciences · 2015Article
- Association of Plasma Heat Shock Protein 70, Interleukin 6, and Creatine Kinase Concentrations in a Healthy, Young Adult Population.Journal of biomarkers · 2015Article
- CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism.Journal of human kinetics · 2013Article
- The genetics of sports injuries and athletic performance.Muscles, ligaments and tendons journal · 2013Review
- Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels.European journal of applied physiology · 2012Article
- Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels.European journal of applied physiology · 2012Article
- Genetic polymorphisms influence runners' responses to the dietary ingestion of antioxidant supplementation based on pequi oil (Caryocar brasiliense Camb.): a before-after study.Genes & nutrition · 2011Article
- Molecular signatures of sprint, strength, and power performance: Integrating genetic, epigenetic, transcriptomic, and telomeric evidence.Science progressReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the association between muscle-specific creatine kinase (CKMM) gene polymorphism and the effects of endurance training on running economy.
methods102 biologically unrelated male volunteers from northern China performed a 5000-m running programme, with an intensity of 95-105% ventilatory threshold. The protocol was undertaken three times per week and lasted for 18 weeks. Running economy indexes were determined by making the participants run on a treadmill before and after the protocol, and the A/G polymorphism in the 3' untranslated region of CKMM was detected by polymerase chain reaction-restricted fragment length polymorphism (NcoI restriction enzyme).
resultsThree expected genotypes for CKMM-NcoI (AA, AG and GG) were observed in the participants. After training, all running economy indexes declined markedly. Change in steady-state consumption of oxygen, change in steady-state consumption of oxygen by mean body weight, change in steady-state consumption of oxygen by mean lean body weight and change in ventilatory volume in AG groups were larger than those in AA and GG groups.
conclusionsThe findings indicate that the CKMM gene polymorphism may contribute to individual running economy responses to endurance training.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.