ReviewInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2007
Just a phase they're going through: the complex interaction of intrinsic high-threshold bursting and gap junctions in the generation of thalamic alpha and theta rhythms.
Review in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Awake alpha bursting emerges as the dynamic working state in a lateral geniculate thalamocortical cell model.PLoS computational biology · 2026Article
- A Systematic Review of Functional Brain Imaging Studies in Neurofibromatosis 1.Neuropsychology review · 2026Review
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- Whole brain functional connectivity: Insights from next generation neural mass modelling incorporating electrical synapses.PLoS computational biology · 2024Article
- Alterations in aperiodic and periodic EEG activity in young children with Down syndrome.Neurobiology of disease · 2024Article
- Developmental trajectories of EEG aperiodic and periodic components in children 2-44 months of age.Nature communications · 2024Article
- Developmental trajectories of EEG aperiodic and periodic components: Implications for understanding thalamocortical development during infancy.bioRxiv : the preprint server for biology · 2024Article
- Spatiotemporal phase slip patterns for visual evoked potentials, covert object naming tasks, and insight moments extracted from 256 channel EEG recordings.Frontiers in integrative neuroscience · 2023Article
- Mean-Field Models for EEG/MEG: From Oscillations to Waves.Brain topography · 2022Article
- One-Year Follow-Up of Healthy Older Adults with Electroencephalographic Risk for Neurocognitive Disorder After Neurofeedback Training.Journal of Alzheimer's disease : JAD · 2022Article
- Inferring a simple mechanism for alpha-blocking by fitting a neural population model to EEG spectra.PLoS computational biology · 2020Article
- Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Central Neuropathic Pain and Profiles of Quantitative Electroencephalography in Multiple Sclerosis Patients.Frontiers in neurology · 2019Article
- Attention Deficit Hyperactivity Disorder in Neurofibromatosis Type 1: Evaluation with a Continuous Performance Test.Journal of clinical neurology (Seoul, Korea) · 2018Article
- Potential synergistic action of 19 schizophrenia risk genes in the thalamus.Schizophrenia research · 2017Review
- Correlated inter-regional variations in low frequency local field potentials and resting state BOLD signals within S1 cortex of monkeys.Human brain mapping · 2016Article
- Exploring Cortical Plasticity and Oscillatory Brain Dynamics via Transcranial Magnetic Stimulation and Resting-State Electroencephalogram.The Malaysian journal of medical sciences : MJMS · 2016Review
- Causal Role of Thalamic Interneurons in Brain State Transitions: A Study Using a Neural Mass Model Implementing Synaptic Kinetics.Frontiers in computational neuroscience · 2016Article
- Relating Alpha Power and Phase to Population Firing and Hemodynamic Activity Using a Thalamo-cortical Neural Mass Model.PLoS computational biology · 2015Article
- Looking for a precursor of spontaneous Sleep Slow Oscillations in human sleep: The role of the sigma activity.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2015Article
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Abstract
Rhythms in the alpha frequency band (8-13 Hz) are a defining feature of the human EEG during relaxed wakefulness and are known to be influenced by the thalamus. In the early stages of sleep and in several neurological and psychiatric conditions alpha rhythms are replaced by slower activity in the theta (3-7 Hz) band. Of particular interest is how these alpha and theta rhythms are generated at the cellular level. Recently we identified a subset of thalamocortical (TC) neurons in the lateral geniculate nucleus (LGN) which exhibit rhythmic high-threshold (>-55 mV) bursting at approximately 2-13 Hz and which are interconnected by gap junctions (GJs). These cells combine to generate a locally synchronized continuum of alpha and theta oscillations, thus providing direct evidence that the thalamus can act as an independent pacemaker of alpha and theta rhythms. Interestingly, GJ coupled pairs of TC neurons can exhibit both in-phase and anti-phase synchrony and will often spontaneously alternate between these two states. This dictates that the local field oscillation amplitude is not simply linked to the extent of cell recruitment into a single synchronized neuronal assembly but also to the degree of destructive interference between dynamic, spatially overlapping, competing anti-phase groups of continuously bursting neurons. Thus, the waxing and waning of thalamic alpha/theta rhythms should not be assumed to reflect a wholesale increase and reduction, respectively, in underlying neuronal synchrony. We argue that these network dynamics might have important consequences for relating changes in the amplitude of EEG alpha and theta rhythms to the activity of thalamic networks.
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