ArticleCancer science2006
Actin-binding protein filamin A is displayed on the surface of human neuroblastoma cells.
Article in Cancer science, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Depletion ofBiomedicines · 2022Article
- Proteomic Profiling of Retinoblastoma-Derived Exosomes Reveals Potential Biomarkers of Vitreous Seeding.Cancers · 2020Article
- Filamin A and DRD2 expression in corticotrophinomas.Pituitary · 2019Article
- Decorin interacting network: A comprehensive analysis of decorin-binding partners and their versatile functions.Matrix biology : journal of the International Society for Matrix Biology · 2016Review
- Filamin A: Insights into its Exact Role in Cancers.Pathology oncology research : POR · 2016Review
- Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability.Leukemia · 2016Article
- Article
- Microaggregate-associated protein involved in invasion of epithelial cells by Mycobacterium avium subsp. hominissuis.Virulence · 2015Article
- Article
- Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A.Oncogenesis · 2014Article
- The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it.Endocrine-related cancer · 2013Review
- Differential expression of filamin A and its clinical significance in breast cancer.Oncology letters · 2013Article
- Distinct regional and subcellular localization of the actin-binding protein filamin A in the mature rat brain.The Journal of comparative neurology · 2012Article
- Article
- Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells.Cancer research · 2010Article
- Functional characterization of filamin a interacting protein 1-like, a novel candidate for antivascular cancer therapy.Cancer research · 2008Article
- Article
- Filamin A increases aggressiveness of human neuroblastoma.Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We previously reported the identification of natural human IgM antibodies, which recognize a M(r) 260 000 surface protein (NB-p260) and induce both complement-mediated cytotoxicity and apoptosis of human neuroblastoma cells. NB-p260 was shown to belong to the family of filamin proteins. Filamin A is a high molecular weight actin-binding protein, previously thought to be only located intracellularly. Here we show that NB cells as well as three NB-unrelated human cell lines express filamin A also on the cell surface. Our findings suggest new biological functions for filamins, including a role as mediators in anti-NB IgM-induced apoptosis, and they add to the growing body of evidence of the interaction of cytoskeletal proteins with the extracellular matrix.
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