Evidence map›Paper›PMID 16998672›Full record

ReviewFamilial cancer2006

Surveillance and management of upper gastrointestinal disease in Familial Adenomatous Polyposis.

Michelle C Gallagher, Robin K S Phillips, Steffen Bulow

Abstract readReview
PubMed Publisher
In one paragraph

Review in Familial cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Prevalence of Gastroduodenal Polyps in Children With Familial Adenomatous Polyposis.Journal of the Canadian Association of Gastroenterology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. FAP related periampullary adenocarcinoma.International journal of surgery case reports · 2013
    Article
  13. Article
  14. Endoscopic management of nonampullary duodenal polyps.Therapeutic advances in gastroenterology · 2012
    Article
  15. Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2011
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle C GallagherThe Polyposis Registry, Cancer Research UK Colorectal Cancer Unit, St Mark's Hospital, Northwick Park, Watford Road, HA1 3UJ, Harrow, UK.
Robin K S Phillips
Steffen Bulow

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Almost all patients affected by Familial Adenomatous polyposis (FAP) will develop foregut as well as hindgut polyps, and following prophylactic colectomy duodenal cancer constitutes one of the leading causes of death in screened populations. Without prophylactic colectomy, FAP patients predictably develop colorectal cancer, but the lifetime risk of upper gastrointestinal cancer is lower, estimated at approximately 5%. Management of the upper gastrointestinal cancer risk is one of the greatest challenges facing clinicians involved in the care of Polyposis families, and with improved survival following prophylactic colectomy, the burden of foregut disease (particularly duodenal adenomatosis) will increase. Until recently, the value of upper gastrointestinal surveillance in FAP populations has been contentious, but with improved understanding of the natural history coupled with developments in surgery, interventional endoscopy and medical therapy, treatment algorithms for duodenal adenomatosis in FAP are becoming clearer.

Indexed as

Adenomatous Polyposis ColiDuodenal NeoplasmsEsophageal NeoplasmsGastrointestinal NeoplasmsHumansPrognosisStomach NeoplasmsUpper Gastrointestinal Tract

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.