ArticleJournal of computational neuroscience2007
Mechanisms of seizure propagation in a cortical model.
Article in Journal of computational neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations.PLoS computational biology · 2015Trial
- A General, Noise-Driven Mechanism for the 1/f-Like Behavior of Neural Field Spectra.Neural computation · 2024Article
- Advanced Modeling and Signal Processing Methods in Brain-Computer Interfaces Based on a Vector of Cyclic Rhythmically Connected Random Processes.Sensors (Basel, Switzerland) · 2023Article
- Patient-Specific Network Connectivity Combined With a Next Generation Neural Mass Model to Test Clinical Hypothesis of Seizure Propagation.Frontiers in systems neuroscience · 2021Article
- Transient neocortical gamma oscillations induced by neuronal response modulation.Journal of computational neuroscience · 2020Article
- Model-based robust suppression of epileptic seizures without sensory measurements.Cognitive neurodynamics · 2020Article
- Multivariate regression methods for estimating velocity of ictal discharges from human microelectrode recordings.Journal of neural engineering · 2017Article
- Suppression of epileptic seizures via Anderson localization.Journal of the Royal Society, Interface · 2017Article
- A probabilistic method for determining cortical dynamics during seizures.Journal of computational neuroscience · 2015Article
- Optogenetic induced epileptiform activity in a model human cortex.SpringerPlus · 2015Article
- Permittivity coupling across brain regions determines seizure recruitment in partial epilepsy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- A probabilistic framework for a physiological representation of dynamically evolving sleep state.Journal of computational neuroscience · 2014Article
- Open loop optogenetic control of simulated cortical epileptiform activity.Journal of computational neuroscience · 2014Article
- Computational modeling of epilepsy for an experimental neurologist.Experimental neurology · 2013Review
- Mechanisms of seizure propagation in 2-dimensional centre-surround recurrent networks.PloS one · 2013Article
- A continuous mapping of sleep states through association of EEG with a mesoscale cortical model.Journal of computational neuroscience · 2011Article
- A model of feedback control for the charge-balanced suppression of epileptic seizures.Journal of computational neuroscience · 2010Article
- Population based models of cortical drug response: insights from anaesthesia.Cognitive neurodynamics · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We consider a mathematical model of mesoscopic human cortical ictal electrical activity. We compare the model results with ictal electrocortical data recorded from three human subjects and show how the two agree. We determine that, in the model system, seizures result from increased connectivity between excitatory and inhibitory cell populations, or from decreased connectivity within either excitatory or inhibitory cell populations. We compare the model results with the disinhibition and 4-AP models of epilepsy and suggest how the model may guide the development of new anticonvulsant therapies.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.