ArticleBiophysical journal2007
The origin of long-range attraction between hydrophobes in water.
Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 63 citations in OpenAlex.
- Context-Aware Hydrophobicity Modeling: HydroMap and FastHydroMap.bioRxiv : the preprint server for biology · 2026Article
- Measuring Molecular Forces With Atomic Force Microscopy 1: Solvent Influence on Hydrophobic Interactions.Microscopy research and technique · 2026Review
- Measuring Colloidal Forces With Atomic Force Microscopy 1: Salt Influence on Hydrophobic and Hydrophilic Interactions.Microscopy research and technique · 2025Review
- Affinity and Inactivation of Bacterial Endotoxins for Medical Device Materials.Biomedical instrumentation & technology · 2023Article
- Isotopically induced variation in the stability of FMN-wrapped carbon nanotubes.Langmuir : the ACS journal of surfaces and colloids · 2013Article
- Functional understanding of solvent structure in GroEL cavity through dipole field analysis.The Journal of chemical physics · 2013Article
- Collagen unfolding accelerates water influx, determining hydration in the interstitial matrix.Biophysical journal · 2012Article
- Theoretical models for surface forces and adhesion and their measurement using atomic force microscopy.International journal of molecular sciences · 2012Review
- Remarkable patterns of surface water ordering around polarized buckminsterfullerene.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Role of hydration force in the self-assembly of collagens and amyloid steric zipper filaments.Journal of the American Chemical Society · 2011Article
- Amyloid oligomer formation probed by water proton magnetic resonance spectroscopy.Biophysical journal · 2011Article
- Role of hydration in collagen recognition by bacterial adhesins.Biophysical journal · 2011Article
- The multiple faces of self-assembled lipidic systems.PMC biophysics · 2009Article
- A new approach for characterizing the intermediate feature of α-chymotrypsin refolding by hydrophobic interaction chromatography.International journal of molecular sciences · 2009Article
- Hydration profiles of amyloidogenic molecular structures.Journal of biological physics · 2008Article
- Hydrophobe-water interactions: methane as a model.Biophysical journal · 2008Article
- How hydrophobic buckminsterfullerene affects surrounding water structure.The journal of physical chemistry. B · 2008Article
- An Integral Equation Study of the Hydrophobic Interaction between Graphene Plates.Journal of chemical theory and computation · 2008Article
- Dehydration-driven solvent exposure of hydrophobic surfaces as a driving force in peptide folding.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When water-coated hydrophobic surfaces meet, direct contacts form between the surfaces, driving water out. However, long-range attractive forces first bring those surfaces close. This analysis reveals the source and strength of the long-range attraction between water-coated hydrophobic surfaces. The origin is in the polarization field produced by the strong correlation and coupling of the dipoles of the water molecules at the surfaces. We show that this polarization field gives rise to dipoles on the surface of the hydrophobic solutes that generate long-range hydrophobic attractions. Thus, hydrophobic aggregation begins with a step in which water-coated nonpolar solutes approach one another due to long-range electrostatic forces. This precursor regime occurs before the entropy increase of releasing the water layers and the short-range van der Waals attraction provide the driving force to "dry out" the contact surface. The effective force of attraction is derived from basic molecular principles, without assumptions of the structure of the hydrophobe-water interaction. The strength of this force can be measured directly from atomic force microscopy images of a hydrophobic molecule tethered to a surface but extending into water, and another hydrophobe attached to an atomic force probe. The phenomenon can be observed in the transverse relaxation rates in water proton magnetic resonance as well. The results shed light on the way water mediates chemical and biological self-assembly, a long outstanding problem.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.