ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2006
Molecular genetic studies of gene identification for osteoporosis: a 2004 update.
Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups.American journal of human genetics · 2009Pooled it
- From Genomics to Metabolomics: Molecular Insights into Osteoporosis for Enhanced Diagnostic and Therapeutic Approaches.Biomedicines · 2024Review
- Pathway and network analysis of genes related to osteoporosis.Molecular medicine reports · 2019Article
- Medical Treatment for Osteoporosis: From Molecular to Clinical Opinions.International journal of molecular sciences · 2019Review
- Icariin regulates the osteoblast differentiation and cell proliferation of MC3T3-E1 cells through microRNA-153 by targeting Runt-related transcription factor 2.Experimental and therapeutic medicine · 2018Article
- Network based subcellular proteomics in monocyte membrane revealed novel candidate genes involved in osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- CC chemokines CCL2, CCL3, CCL4 and CCL5 are elevated in osteoporosis patients.Journal of biomedical research · 2017Article
- Quantitative proteomics and integrative network analysis identified novel genes and pathways related to osteoporosis.Journal of proteomics · 2016Article
- Association of COL1A1 polymorphisms with osteoporosis: a meta-analysis of clinical studies.International journal of clinical and experimental medicine · 2015Article
- C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention.Journal of translational medicine · 2014Article
- Genome-wide Association Studies for Osteoporosis: A 2013 Update.Journal of bone metabolism · 2014Review
- Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.Physiological reviews · 2014Review
- Polymorphisms in SPARC and coal workers' pneumoconiosis risk in a Chinese population.PloS one · 2014Article
- Genetic influence on bone phenotypes and body composition: a Swedish twin study.Journal of bone and mineral metabolism · 2013Article
- A haplotype derived from the common variants at the -1997G/T and Sp1 binding site of the COL1A1 gene influences risk of postmenopausal osteoporosis in India.Rheumatology international · 2013Article
- Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed.The Journal of clinical endocrinology and metabolism · 2012Review
- Identification of genes for complex diseases by integrating multiple types of genomic data.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2012Article
- Identification of genes for complex diseases using integrated analysis of multiple types of genomic data.PloS one · 2012Article
- MiR-133a in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis.PloS one · 2012Article
- Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.PloS one · 2011Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This review summarizes comprehensively the most important and representative molecular genetics studies of gene identification for osteoporosis published up to the end of December 2004. It is intended to constitute a sequential update of our previously published review covering the available data up to the end of 2002. Evidence from candidate gene association studies and genome-wide linkage studies in humans, as well as quantitative trait locus mapping animal models are reviewed separately. Studies of transgenic and knockout mice models relevant to osteoporosis are summarized. An important extension of this update is incorporation of functional genomic studies (including DNA microarrays and proteomics) on osteogenesis and osteoporosis, in light of the rapid advances and the promising prospects of the field. Comments are made on the most notable findings and representative studies for their potential influence and implications on our present understanding of genetics of osteoporosis. The format adopted by this review should be ideal for accommodating future new advances and studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.