ArticleProceedings of the National Academy of Sciences of the United States of America2006
Sperm competition enhances functional capacity of mammalian spermatozoa.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
45 citing papers in PubMed, 123 citations in OpenAlex.
- Epididymal sperm maturation in mouse species with differing levels of sperm competition†.Biology of reproduction · 2026Article
- Sperm dynamics in the female reproductive tract and their role in regulating fertility.The Journal of reproduction and development · 2026Review
- The Olfactory Receptor Olfr25 Mediates Sperm Dysfunction Induced by Low-Dose Bisphenol A through the CatSper-CaToxics · 2024Article
- The rapidly evolving X-linkedeLife · 2024Article
- The Rapidly Evolving X-linkedbioRxiv : the preprint server for biology · 2024Article
- Spokes and barrels tune the asymmetric beating of mammalian sperm flagella.Nature structural & molecular biology · 2023Article
- Effect of High Viscosity on Energy Metabolism and Kinematics of Spermatozoa from Three Mouse Species Incubated under Capacitating Conditions.International journal of molecular sciences · 2022Article
- Intraspecific variation in male mating strategies in an African ground squirrel (Ecology and evolution · 2022Article
- Energy Metabolism and Hyperactivation of Spermatozoa from Three Mouse Species under Capacitating Conditions.Cells · 2022Article
- Sperm bauplan and function and underlying processes of sperm formation and selection.Physiological reviews · 2022Review
- Capacitation promotes a shift in energy metabolism in murine sperm.Frontiers in cell and developmental biology · 2022Article
- Article
- Of mice and women: advances in mammalian sperm competition with a focus on the female perspective.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Meiotic Nuclear Architecture in Distinct Mole Vole Hybrids with Robertsonian Translocations: Chromosome Chains, Stretched Centromeres, and Distorted Recombination.International journal of molecular sciences · 2020Article
- Natural Variation and Genetic Determinants ofGenetics · 2019Article
- Article
- Parallel Evolution of Sperm Hyper-Activation Ca2+ Channels.Genome biology and evolution · 2017Article
- Comparative Sperm Proteomics in Mouse Species with Divergent Mating Systems.Molecular biology and evolution · 2017Article
- A cost for high levels of sperm competition in rodents: increased sperm DNA fragmentation.Proceedings. Biological sciences · 2016Article
- Pre- and Postcopulatory Traits of Salvator Male Lizards in Allopatry and Sympatry.Scientifica · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When females mate promiscuously, sperm from rival males compete within the female reproductive tract to fertilize ova. Sperm competition is a powerful selective force that has shaped sexual behavior, sperm production, and sperm morphology. However, nothing is known about the influence of sperm competition on fertilization-related processes, because it has been assumed that sperm competition only involves a race to reach the site of fertilization. We compared four closely related rodent species with different levels of sperm competition to examine whether there are differences in the proportion of spermatozoa that become ready to interact with the ovum ("capacitated") and in the proportion of spermatozoa that experience the acrosome reaction in response to a natural stimulant. Our results show that differences between species in levels of sperm competition were associated with the proportion of spermatozoa that undergo capacitation and with the proportion of spermatozoa that respond to progesterone, an ovum-associated signal. Sperm competition thus favors a larger population of spermatozoa that are competent to fertilize, and spermatozoa that are more sensitive to the signals emitted by the ovum and that may penetrate the ova vestments more rapidly. These results suggest that, contrary to previous assumptions, competition between spermatozoa from rival males continues at the site of fertilization. These findings may have further evolutionary implications because the enhanced competitiveness of spermatozoa during fertilization may increase the risk of polyspermy to females. This could lead to antagonistic coevolution between the sexes and may contribute to the explanation of the rapid divergence observed in fertilization-related traits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.