ReviewJournal of cellular and molecular medicine
Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- BORIS: a key regulator of cancer stemness.Cancer cell international · 2018Review
- Depletion of CTCF in Breast Cancer Cells Selectively Induces Cancer Cell Death via p53.Journal of Cancer · 2017Article
- Article
- Three-dimensional regulation of transcription.Protein & cell · 2015Review
- A novel mechanism for CTCF in the epigenetic regulation of Bax in breast cancer cells.Neoplasia (New York, N.Y.) · 2013Article
- Disruption of CTCF at the miR-125b1 locus in gynecological cancers.BMC cancer · 2012Article
- A cell cycle role for the epigenetic factor CTCF-L/BORIS.PloS one · 2012Article
- Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.BMC cancer · 2011Article
- Interruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic imprinting of human insulin-like growth factor II.The Journal of cell biology · 2011Article
- CTCF promotes muscle differentiation by modulating the activity of myogenic regulatory factors.The Journal of biological chemistry · 2011Article
- BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells.Nucleic acids research · 2011Article
- Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines.Oncogene · 2010Article
- Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation.Molecular and cellular biology · 2010Article
- Intergenic, gene terminal, and intragenic CpG islands in the human genome.BMC genomics · 2010Article
- Does CTCF mediate between nuclear organization and gene expression?BioEssays : news and reviews in molecular, cellular and developmental biology · 2010Review
- Comparative methylation of ERVWE1/syncytin-1 and other human endogenous retrovirus LTRs in placenta tissues.DNA research : an international journal for rapid publication of reports on genes and genomes · 2009Article
- Prognostic role of global DNA-methylation and histone acetylation in pT1a clear cell renal carcinoma in partial nephrectomy specimens.Journal of cellular and molecular medicine · 2009Article
- CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop.Molecular and cellular biology · 2008Article
- Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males.BMC medical genomics · 2008Article
- Epigenetics in acute myeloid leukemia.Seminars in oncology · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic and epigenetic regulations are essential mechanisms that ensure proper early and subsequent mammalian programming of diverse cellular processes. These mechanisms affect transcriptional regulation, stem cell determination and cell cycle control, including senescence and aging. It is not surprising that perturbation of the exquisite balance between genetic and epigenetic regulation can lead to diverse diseases, including cancer. Histone covalent modifications and DNA methylation do not explain all epigenetic phenomena. We describe a previously unsuspected epigenetic factor and propose the incorporation of the 11-zinc finger CCCTC-binding factor, known as CTCF as a novel and multifunctional epigenetic regulator.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.