ArticleMedical immunology (London, England)2006
Chronic Granulomatous Disease; fundamental stages in our understanding of CGD.
Article in Medical immunology (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 86 citations in OpenAlex.
- The Multiple Faces of Nitric Oxide in Chronic Granulomatous Disease: A Comprehensive Update.Biomedicines · 2022Review
- Precision medicine: The use of tailored therapy in primary immunodeficiencies.Frontiers in immunology · 2022Review
- Metabolic reprogramming of myeloid-derived suppressor cells: An innovative approach confronting challenges.Journal of leukocyte biology · 2021Review
- Life-Threatening Infections Due to Live-Attenuated Vaccines: Early Manifestations of Inborn Errors of Immunity.Journal of clinical immunology · 2019Review
- Article
- Epic Immune Battles of History: Neutrophils vs.Frontiers in cellular and infection microbiology · 2017Review
- Lack of p47(phox) in Akita Diabetic Mice Is Associated with Interstitial Pneumonia, Fibrosis, and Oral Inflammation.The American journal of pathology · 2016Article
- The antioxidants dilemma: are they potentially immunosuppressants and carcinogens?Frontiers in physiology · 2014Article
- Myeloperoxidase: a front-line defender against phagocytosed microorganisms.Journal of leukocyte biology · 2013Review
- Case 1: The formula dance.Paediatrics & child health · 2012Article
- TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Degranulation deconstructed.The Journal of clinical investigation · 2012Article
- Flavonoids inhibit the respiratory burst of neutrophils in mammals.Oxidative medicine and cellular longevity · 2012Review
- Role of p47phox in antigen-presenting cell-mediated regulation of humoral immunity in mice.The American journal of pathology · 2011Article
- A difficult case of Crohn's disease?BMJ case reports · 2011Article
- Early enhanced local neutrophil recruitment in peritonitis-induced sepsis improves bacterial clearance and survival.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- The clinical utility of molecular diagnostic testing for primary immune deficiency disorders: a case based review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2010Article
- Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
- Alternaria infectoria brain abscess in a child with chronic granulomatous disease.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2009Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been 50 years since chronic granulomatous disease was first reported as a disease which fatally affected the ability of children to survive infections. Various milestone discoveries from the insufficient ability of patients' leucocytes to destroy microbial particles to the underlying genetic predispositions through which the disease is inherited have had important consequences. Longterm antibiotic prophylaxis has helped to fight infections associated with chronic granulomatous disease while the steady progress in bone marrow transplantation and the prospect of gene therapy are hailed as long awaited permanent treatment options. This review unearths the important findings by scientists that have led to our current understanding of the disease.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.