ArticleEcotoxicology (London, England)2006
Genetic diversity and structure of an estuarine fish (Fundulus heteroclitus) indigenous to sites associated with a highly contaminated urban harbor.
Article in Ecotoxicology (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 75 citations in OpenAlex.
- Urbanisation Is Associated With Reduced Genetic Diversity in Marine Fish Populations.Molecular ecology · 2025Review
- Urbanization and distance shape population structure inJournal of urban ecology · 2024Article
- Evolutionary responses of marine organisms to urbanized seascapes.Evolutionary applications · 2021Article
- Small coastal streams-Critical reservoirs of genetic diversity for trout (Ecology and evolution · 2020Article
- Bioaccumulation and effects of dietary exposure to the alternative flame retardant, bis(2-ethylhexyl) tetrabromophthalate (TBPH), in the Atlantic killifish, Fundulus heteroclitus.Environmental toxicology and chemistry · 2018Article
- When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Evolutionary applications · 2017Review
- Evolutionary consequences of historical metal contamination for natural populations of Chironomus riparius (Diptera: Chironomidae).Ecotoxicology (London, England) · 2017Article
- Urban driven phenotypic changes: empirical observations and theoretical implications for eco-evolutionary feedback.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Article
- Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus).Aquatic toxicology (Amsterdam, Netherlands) · 2015Article
- The Elizabeth River Story: A Case Study in Evolutionary Toxicology.Journal of toxicology and environmental health. Part B, Critical reviews · 2015Review
- Targeted approach to identify genetic loci associated with evolved dioxin tolerance in Atlantic killifish (Fundulus heteroclitus).BMC evolutionary biology · 2014Article
- Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats.BMC evolutionary biology · 2014Article
- Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences.BMC genomics · 2013Article
- Common mechanism underlies repeated evolution of extreme pollution tolerance.Proceedings. Biological sciences · 2012Article
- Directional genetic selection by pulp mill effluent on multiple natural populations of three-spined stickleback (Gasterosteus aculeatus).Ecotoxicology (London, England) · 2011Article
- Embryonic gene expression among pollutant resistant and sensitive Fundulus heteroclitus populations.Aquatic toxicology (Amsterdam, Netherlands) · 2010Article
- SNP identification, verification, and utility for population genetics in a non-model genus.BMC genetics · 2010Article
- Evolution of tolerance to PCBs and susceptibility to a bacterial pathogen (Vibrio harveyi) in Atlantic killifish (Fundulus heteroclitus) from New Bedford (MA, USA) harbor.Environmental pollution (Barking, Essex : 1987) · 2009Article
- Signatures of selection in natural populations adapted to chronic pollution.BMC evolutionary biology · 2008Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intense selection on isolated populations can cause loss of genetic diversity, which if persistent, reduces adaptive potential and increases extinction probability. Phenotypic evidence of inherited tolerance suggests that polychlorinated biphenyls (PCBs), have acted as strong selective agents on populations of a non-migratory fish, Fundulus heteroclitus, indigenous to heavily contaminated sites. To evaluate population genetic structure and test for effects of intense, multi-generational PCB contamination on genetic diversity, we used AFLP analysis on fish collected from six sites along the east coast of North America that varied widely in PCB contamination. The sites included a heavily contaminated urban harbor (New Bedford, MA), an adjacent moderately contaminated sub-estuary (Buzzards Bay, MA), and an uncontaminated estuary 60 km away (Narragansett, RI). AFLP markers distinguished populations at moderate and small scales, suggesting genetic differentiation at distances of 2 km or less. Genetic diversity did not differ across the study sites. Genome-wide diversity may have been preserved because of large effective population sizes and/or because the mechanism for genetic adaptation to these contaminants affected only a small number of loci. Alternatively, loss in diversity may have been restored with moderate levels of migration and relatively short generation time for this species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.