Evidence map›Paper›PMID 16988279›Full record

ArticleInfection and immunity2006

Overexpression, purification, characterization, and pathogenicity of Vibrio harveyi hemolysin VHH.

Yingbin Zhong, Xiao-Hua Zhang, Jixiang Chen, Zhenghao Chi, Boguang Sun, Yun Li, Brian Austin

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 62 citations in OpenAlex.

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  11. Marine life science & technology · 2020
    Review
  12. Structural analysis of aThe Journal of biological chemistry · 2019
    Article
  13. Article
  14. Bacterial Sphingomyelinases and Phospholipases as Virulence Factors.Microbiology and molecular biology reviews : MMBR · 2016
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yingbin ZhongDepartment of Marine Biology, Ocean University of China, 5 Yushan Road, Qingdao 266003, People's Republic of China.
Xiao-Hua Zhang
Jixiang Chen
Zhenghao Chi
Boguang Sun
Yun Li
Brian Austin
Ocean University of China · CNHeriot-Watt University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vibrio harveyi VHH hemolysin is a putative pathogenicity factor in fish. In this study, the hemolysin gene vhhA was overexpressed in Escherichia coli, and the purified VHH was characterized with regard to pH and temperature profiles, phospholipase activity, cytotoxicity, pathogenicity to flounder, and the signal peptide.

Indexed as

Amino Acid SequenceAnimalsBacterial ProteinsBase SequenceEscherichia coliFlounderHemolysin ProteinsMolecular Sequence DataPhospholipasesTemperatureVibrioBacterial ProteinsHemolysin Proteinshemolysin, VibrioPhospholipases

Identifiers

PMID16988279
PMCPMC1594901
OpenAlexW2106077705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.