ArticleGenetics2006
The meiotic bouquet promotes homolog interactions and restricts ectopic recombination in Schizosaccharomyces pombe.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Rewiring for movements in meiotic prophase: regulators, roles, and evolutionary pathways.Current opinion in genetics & development · 2025Review
- Review
- The Meiosis-Specific Crs1 Cyclin Is Required for Efficient S-Phase Progression and Stable Nuclear Architecture.International journal of molecular sciences · 2021Article
- High Temporal Resolution 3D Live-Cell Imaging of Budding Yeast Meiosis Defines Discontinuous Actin/Telomere-Mediated Chromosome Motion, Correlated Nuclear Envelope Deformation and Actin Filament Dynamics.Frontiers in cell and developmental biology · 2021Article
- CDK Regulation of Meiosis: Lessons fromGenes · 2020Review
- Chromosome Dynamics Regulating Genomic Dispersion and Alteration of Nucleolus Organizer Regions (NORs).Cells · 2020Review
- Meiotic chromosomes in motion: a perspective from Mus musculus and Caenorhabditis elegans.Chromosoma · 2019Article
- Genes Important forGenetics · 2018Article
- Article
- The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast.Cell discovery · 2017Article
- Meiotic cohesin-based chromosome structure is essential for homologous chromosome pairing in Schizosaccharomyces pombe.Chromosoma · 2016Article
- Recombination, Pairing, and Synapsis of Homologs during Meiosis.Cold Spring Harbor perspectives in biology · 2015Review
- The telomere bouquet regulates meiotic centromere assembly.Nature cell biology · 2015Article
- Chromosome movement in meiosis I prophase of Caenorhabditis elegans.Chromosoma · 2014Review
- The Chromosomal Courtship Dance-homolog pairing in early meiosis.Current opinion in cell biology · 2014Review
- Chromosome pairing and synapsis during Caenorhabditis elegans meiosis.Current opinion in cell biology · 2013Review
- Multiple opposing constraints govern chromosome interactions during meiosis.PLoS genetics · 2013Article
- Sustained and rapid chromosome movements are critical for chromosome pairing and meiotic progression in budding yeast.Genetics · 2011Article
- Dynamic chromosome movements during meiosis: a way to eliminate unwanted connections?Trends in cell biology · 2009Review
- Cytoskeletal forces span the nuclear envelope to coordinate meiotic chromosome pairing and synapsis.Cell · 2009Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Chromosome architecture undergoes extensive, programmed changes as cells enter meiosis. A highly conserved change is the clustering of telomeres at the nuclear periphery to form the "bouquet" configuration. In the fission yeast Schizosaccharomyces pombe the bouquet and associated nuclear movement facilitate initial interactions between homologs. We show that Bqt2, a meiosis-specific protein required for bouquet formation, is required for wild-type levels of homolog pairing and meiotic allelic recombination. Both gene conversion and crossing over are reduced and exhibit negative interference in bqt2Delta mutants, reflecting reduced homolog pairing. While both the bouquet and nuclear movement promote pairing, only the bouquet restricts ectopic recombination (that between dispersed repetitive DNA). We discuss mechanisms by which the bouquet may prevent deleterious translocations by restricting ectopic recombination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.