Evidence map›Paper›PMID 16988070›Full record

SynthesisObesity (Silver Spring, Md.)2006

The evolution of very-low-calorie diets: an update and meta-analysis.

Adam Gilden Tsai, Thomas A Wadden

3 registry-linked trialsAbstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Obesity (Silver Spring, Md.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 112 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 10 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02910154 nacompletedstarted 2016, after this paper: background citation

Comprehensive Treatment of Angina in Women With Microvascular Dysfunction - a Proof of Concept Study of the iPower Cohort

Ran2016Enrolled62Registered outcomes9Posted comparisons0ConditionsAngina Pectoris, Coronary Microvascular DiseaseArmsdiet, Medication (with statin and ACE-inhibition), training
PMID 19878986PMID 19433695PMID 19712795PMID 19833255PMID 24071763PMID 16368303PMID 16458167PMID 16923752PMID 17430682PMID 18370439PMID 19231324PMID 19351944other papers from this trial
Open the trial in the graph
NCT01803737 nacompletednot on this mapstarted 2013, after this paper: background citation

Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults

TypeinterventionalSponsorUniversity of PittsburghRan2013 to 2013Enrolled26ConditionsWeight LossArmsStandard Behavioral Weight Loss Intervention (SBWL), Campaign Intervention (CI)
NCT06275347 nacompletednot on this mapstarted 2021, after this paper: background citation

Comparative Study of the Response to Weight Loss and Metabolic Conditions Using Two Non-pharmacological Nutritional Programs

TypeinterventionalSponsorUniversidad VeracruzanaRan2021 to 2023Enrolled88ConditionsObesityArmsLow-fat normoprotein Controlled Ketogenic Diet., Hypocaloric Balanced Diet
3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 10 syntheses or guidelines pooled it, 370 citations in OpenAlex.

  1. Pooled it
  2. Obesity in South and Southeast Asia-A new consensus on care and management.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Guideline
  3. Effects of total diet replacement programs on mental well-being: A systematic review with meta-analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Pooled it
  8. European Guidelines for Obesity Management in Adults.Obesity facts · 2015 · on this map
    Guideline
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Acceptability of a very-low-energy diet in Type 2 diabetes: patient experiences and behaviour regulation.Diabetic medicine : a journal of the British Diabetic Association · 2017
    Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Short-term changes after a weight reduction intervention in advanced diabetic nephropathy.Clinical journal of the American Society of Nephrology : CJASN · 2013
    Trial
  20. Trial

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adam Gilden TsaiDepartment of Psychiatry, Center for Weight and Eating Disorders, University of Pennsylvania School of Medicine, 3535 Market Street, Suite 3029, Philadelphia, PA 19104, USA.
Thomas A Wadden
University of Pennsylvania · US

Funding

IMPROVING THE EFFECTIVENESS OF OBESITY MANAGEMENTK24DK065018 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WADDEN, THOMAS A. · 2003 to 2013
$1.4M
NIDDK NIH HHS K24-DK-065018
6 · The paper itself

Abstract

objectiveVery-low-calorie diets (VLCDs), providing <800 kcal/d, have been used since the 1970s to induce rapid weight loss. Previous reviews of the literature have disagreed concerning the relative efficacy of VLCDs vs. conventional low-calorie diets (LCDs) for achieving long-term weight loss. RESEARCH METHODS AND PROCEDURES: We sought to update findings on the clinical use, safety, and efficacy of VLCDs and to perform a meta-analysis of randomized trials that compared the long-term efficacy of LCDs and VLCDs. Original research articles were retrieved by a Medline search and from prior reviews of VLCDs. Trials were included only if they were randomized comparisons of LCDs and VLCDs and included a follow-up assessment at least 1 year after maximum weight loss. Data were abstracted by both authors regarding: duration of VLCD, total length of treatment, attrition, short- and long-term weight loss, changes in weight-related comorbidities, and adverse effects.

resultsSix randomized trials were found that met inclusion criteria. VLCDs, compared with LCDs, induced significantly greater short-term weight losses (16.1 +/- 1.6% vs. 9.7 +/- 2.4% of initial weight, respectively; p = 0.0001) but similar long-term losses (6.3 +/- 3.2% vs. 5.0 +/- 4.0%, respectively; p > 0.2). Attrition was similar with VLCD and LCD regimens. DISCUSSION: VLCDs did not produce greater long-term weight losses than LCDs. In the United States, the use of liquid meal replacements as part of a 1000 to 1500 kcal/d diet may provide an effective and less expensive alternative to VLCDs. In Europe, VLCDs are used with less intensive medical supervision than in the United States, which reduces the cost of this approach.

Indexed as

Caloric RestrictionDiet, ReducingHumansObesityRandomized Controlled Trials as TopicTime FactorsWeight Loss

Identifiers

PMID16988070
OpenAlexW2083140947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.