Evidence map›Paper›PMID 16988021›Full record

ArticleJournal of clinical microbiology2006

Presence of copper- and zinc-containing superoxide dismutase in commensal Haemophilus haemolyticus isolates can be used as a marker to discriminate them from nontypeable H. influenzae isolates.

W W Mary Fung, Clíona A O'Dwyer, Sunita Sinha, Aimee L Brauer, Timothy F Murphy, J Simon Kroll, Paul R Langford

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Identification and Characterization of "Journal of clinical microbiology · 2019
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Haemophilus influenzae and oxidative stress.Frontiers in cellular and infection microbiology · 2012
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

W W Mary FungDepartment of Paediatrics, Division of Medicine, Imperial College, St Mary's Campus, London W2 1PG, United Kingdom.
Clíona A O'Dwyer
Sunita Sinha
Aimee L Brauer
Timothy F Murphy
J Simon Kroll
Paul R Langford

Funding

Persistent H. influenzae in COPD - virulence, vaccines and antibiotic resistanceR01AI019641 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 1985 to 2023
$7.9M
NIAID NIH HHS AI19641NIAID NIH HHS R01 AI019641Wellcome Trust
6 · The paper itself

Abstract

Respiratory isolates of Haemophilus haemolyticus are regularly misclassified as nontypeable (NT) Haemophilus influenzae due to an aberrant hemolytic reaction on blood agar, with implications for treatment. The presence of sodC or its cognate protein, copper-zinc superoxide dismutase, can distinguish respiratory isolates of H. haemolyticus from NT H. influenzae with 100% accuracy.

Indexed as

BiomarkersHaemophilusHaemophilus influenzaeHemolysisSuperoxide DismutaseBiomarkersSuperoxide Dismutase

Identifiers

PMID16988021
PMCPMC1698342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.