ReviewTraffic (Copenhagen, Denmark)2006
Regulation of cytoskeletal dynamics at the immune synapse: new stars join the actin troupe.
Review in Traffic (Copenhagen, Denmark), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 76 citations in OpenAlex.
- Disulfidptosis and Its Hub Gene Slc3a2 Involved in Ulcerative Colitis Pathogenesis, Disease Progression, and Patient Responses to Biologic Therapies.International journal of molecular sciences · 2024Article
- Hem-1 regulates protective humoral immunity and limits autoantibody production in a B cell-specific manner.JCI insight · 2022Article
- How cytosolic compartments play safeguard functions against neuroinflammation and cell death in cerebral ischemia.Metabolic brain disease · 2021Review
- Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+ T cells post peptide loading.PLoS pathogens · 2020Article
- Actin cytoskeleton in mesenchymal-to-amoeboid transition of cancer cells.International review of cell and molecular biology · 2020Review
- In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy.iScience · 2019Article
- The Actin Cytoskeleton and Actin-Based Motility.Cold Spring Harbor perspectives in biology · 2018Review
- Mechanosensing in the immune response.Seminars in cell & developmental biology · 2017Review
- Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation.Frontiers in immunology · 2017Review
- Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.Scientific reports · 2016Article
- Type II PtdIns 4-kinase β associates with CD4-p56lck complex and is involved in CD4 receptor signaling.Molecular and cellular biochemistry · 2014Article
- T cell responses: naive to memory and everything in between.Advances in physiology education · 2013Article
- Cofilin: a redox sensitive mediator of actin dynamics during T-cell activation and migration.Immunological reviews · 2013Review
- The actin-bundling protein L-plastin supports T-cell motility and activation.Immunological reviews · 2013Review
- Ultrastructure of protrusive actin filament arrays.Current opinion in cell biology · 2013Review
- Plasma membrane calcium ATPase activity is regulated by actin oligomers through direct interaction.The Journal of biological chemistry · 2013Article
- 4D non-uniformly sampled HCBCACON and ¹J(NCα)-selective HCBCANCO experiments for the sequential assignment and chemical shift analysis of intrinsically disordered proteins.Journal of biomolecular NMR · 2012Article
- Aging, immunosenescence and membrane rafts: the lipid connection.Longevity & healthspan · 2012Review
- Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF.PloS one · 2012Article
- Immunoinhibitory adapter protein Src homology domain 3 lymphocyte protein 2 (SLy2) regulates actin dynamics and B cell spreading.The Journal of biological chemistry · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Reorganization of actin cytoskeletal dynamics plays a critical role in controlling T-lymphocyte activation and effector functions. Interaction of T-cell receptors (TCR) with appropriate major histocompatibility complex-peptide complexes on antigen-presenting cells results in the activation of signaling cascades, leading to the accumulation of F-actin at the cell-cell contact site. This event is required for the formation and stabilization of the immune synapse (IS), a cellular structure essential for the modulation of T-cell responses. Analysis of actin cytoskeletal dynamics following engagement of the TCR has largely focused on the Arp2/3 regulator, WASp, because of its early identification and its association with human disease. However, recent studies have shown equally important roles for several additional actin regulatory proteins. In this review, we turn the spotlight on the expanding cast of actin regulatory proteins, which co-ordinate actin dynamics at the IS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.