Evidence map›Paper›PMID 16983602›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2006

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult.

Charles Y Chiu, Silvi Rouskin, Anita Koshy, Anatoly Urisman, Kael Fischer, Shigeo Yagi, David Schnurr, Paul B Eckburg, Lucy S Tompkins, Brian G Blackburn and 4 more

Abstract readCase Reports
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Biographical Feature: Charles Y. Chiu, M.D., Ph.D.Journal of clinical microbiology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
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  13. Article
  14. Virus discovery: one step beyond.Current opinion in virology · 2013
    Article
  15. Viral surveillance and discovery.Current opinion in virology · 2013
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charles Y ChiuDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.
Silvi Rouskin
Anita Koshy
Anatoly Urisman
Kael Fischer
Shigeo Yagi
David Schnurr
Paul B Eckburg
Lucy S Tompkins
Brian G Blackburn
Jason D Merker
Bruce K Patterson
Don Ganem
Joseph L DeRisi

Funding

BIOLOGY OF INFECTIOUS DISEASES TRAINING PROGRAMT32AI007641 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY · 2000 to 2026
$6.9M
NIAID NIH HHS T32 AI007641NIAID NIH HHS T32-AI07641
6 · The paper itself

Abstract

A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness. The virus was identified in an endotracheal aspirate specimen, and the microarray results were confirmed by specific polymerase chain reaction and serological analysis for HPIV-4. Conventional clinical laboratory testing using an extensive panel of microbiological tests failed to yield a diagnosis. This case suggests that the potential severity of disease caused by HPIV-4 in adults may be greater than previously appreciated and illustrates the clinical utility of a microarray for broad-based viral pathogen screening.

Indexed as

AdultBronchiolitis, ViralFemaleHumansOligonucleotide Array Sequence AnalysisParainfluenza Virus 4, HumanPneumonia, ViralRubulavirus InfectionsSerologic TestsTomography Scanners, X-Ray Computed

Identifiers

PMID16983602
PMCPMC7108001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.