Evidence map›Paper›PMID 16980813›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2006

Population-based study of the prevalence of family history of cancer: implications for cancer screening and prevention.

Scott D Ramsey, Paula Yoon, Ramal Moonesinghe, Muin J Khoury

Open access · bronzeAbstract read
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 160 citations in OpenAlex.

  1. Pooled it
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  5. The effect of a school-based educational intervention on gender differences in reported family cancer history.Journal of cancer education : the official journal of the American Association for Cancer Education · 2008
    Trial
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  10. Family History in the Context of CKD.Journal of the American Society of Nephrology : JASN · 2025
    Article
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  13. Applying ONCO-RADS to whole-body MRI cancer screening in a retrospective cohort of asymptomatic individuals.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Scott D RamseyFred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, PO Box 19024, Seattle, WA 98109, USA.
Paula Yoon
Ramal Moonesinghe
Muin J Khoury
Centers for Disease Control and Prevention · USUniversity of Washington · US

Funding

SEATTLE FAMILIAL COLORECTAL CANCER REGISTRYU01CA074794 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI NEWCOMB, POLLY A · 1997 to 2007
$14.1M
EVALUATING USE OF GENETIC INFORMATION: A MODEL PROCESSR01HG002263 · NHGRI · UNIVERSITY OF WASHINGTON · PI BURKE, WYLIE G · 2001 to 2003
$1.4M
A Genetic Screening Policy Model for Colorectal CancerR01CA114794 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RAMSEY, SCOTT D · 2004 to 2006
$1.0M
NCI NIH HHS R01 CA114794NCI NIH HHS U01 CA074794NHGRI NIH HHS R01 HG002263NHGRI NIH HHS R01 HG 002941NHGRI NIH HHS R01 HG 02263
6 · The paper itself

Abstract

purposeFamily history assessment is gaining importance as a potential public health tool to help determine susceptibility to common cancers. Population-based data on the prevalence of having a family history of common cancers are scant.

methodsWe queried survey questions from the National Health Interview Survey, an annual nationwide survey of approximately 36,000 households in the United States, to determine the prevalence of persons reporting one or more first-degree relatives with breast, colorectal, lung, prostate, or ovarian cancer.

resultsBreast cancer was the most common condition noted for family members (7.74% of respondents), followed by lung cancer (7.10%), colorectal cancer (4.96%), prostate cancer (4.68%), and ovarian cancer (1.79%). A family history of cancer was more commonly reported by older persons, whites, women, and high-income groups.

conclusionA substantial proportion of persons in the United States report having a close family member with cancer, and thus may be eligible for earlier or more aggressive cancer screening services.

Indexed as

FamilyAdultAgedBreast NeoplasmsColorectal NeoplasmsCross-Sectional StudiesFemaleHumansLung NeoplasmsMaleMass ScreeningMiddle AgedNeoplasmsOvarian NeoplasmsProstatic NeoplasmsRisk Factors

Identifiers

PMID16980813
PMCPMC2726801
OpenAlexW2168342057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.