ArticleThe Plant cell2006
The chromatin assembly factor subunit FASCIATA1 is involved in homologous recombination in plants.
Article in The Plant cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed, 127 citations in OpenAlex.
- Article
- Regulation of heterochromatin organization in plants.Journal of plant research · 2024Review
- In-section Click-iT detection and super-resolution CLEM analysis of nucleolar ultrastructure and replication in plants.Nature communications · 2024Article
- Mitotic inheritance of genetic and epigenetic information via the histone H3.1 variant.Current opinion in plant biology · 2023Review
- Histone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis.Nature communications · 2022Article
- DNA polymerase epsilon binds histone H3.1-H4 and recruits MORC1 to mediate meiotic heterochromatin condensation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- G2/M-checkpoint activation in fasciata1 rescues an aberrant S-phase checkpoint but causes genome instability.Plant physiology · 2021Article
- The rDNA Loci-Intersections of Replication, Transcription, and Repair Pathways.International journal of molecular sciences · 2021Review
- Nuclear Chaperone ASF1 is Required for Gametogenesis in Arabidopsis thaliana.Scientific reports · 2019Article
- CRISPR/Cas-mediated gene targeting in plants: finally a turn for the better for homologous recombination.Plant cell reports · 2019Review
- The genetic architecture of genome-wide recombination rate variation in allopolyploid wheat revealed by nested association mapping.The Plant journal : for cell and molecular biology · 2018Article
- Auxin decreases chromatin accessibility through the TIR1/AFBs auxin signaling pathway in proliferative cells.Scientific reports · 2018Article
- Review
- Overexpression of chromatin assembly factor-1/p60 predicts biological behaviour of laryngeal carcinomas.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2017Article
- The Absence of the Arabidopsis Chaperone Complex CAF-1 Produces Mitotic Chromosome Abnormalities and Changes in the Expression Profiles of Genes Involved in DNA Repair.Frontiers in plant science · 2017Article
- Variation of 45S rDNA intergenic spacers in Arabidopsis thaliana.Plant molecular biology · 2016Article
- The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana.PLoS genetics · 2016Article
- A DNA2 Homolog Is Required for DNA Damage Repair, Cell Cycle Regulation, and Meristem Maintenance in Plants.Plant physiology · 2016Article
- Maintaining Epigenetic Inheritance During DNA Replication in Plants.Frontiers in plant science · 2016Review
- Influence of Human p53 on Plant Development.PloS one · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA replication in cycling eukaryotic cells necessitates the reestablishment of chromatin after nucleosome redistribution from the parental to the two daughter DNA strands. Chromatin assembly factor 1 (CAF-1), a heterotrimeric complex consisting of three subunits (p150/p60/p48), is one of the replication-coupled assembly factors involved in the reconstitution of S-phase chromatin. CAF-1 is required in vitro for nucleosome assembly onto newly replicated chromatin in human cells and Arabidopsis thaliana, and defects in yeast (Saccharomyces cerevisiae) affect DNA damage repair processes, predominantly those involved in genome stability. However, in vivo chromatin defects of caf-1 mutants in higher eukaryotes are poorly characterized. Here, we show that fasciata1-4 (fas1-4), a new allele of the Arabidopsis fas1 mutant defective in the p150 subunit of CAF-1, has a severe developmental phenotype, reduced heterochromatin content, and a more open conformation of euchromatin. Most importantly, homologous recombination (HR), a process involved in maintaining genome stability, is increased dramatically in fas1-4, as indicated by a 96-fold stimulation of intrachromosomal HR. Together with the open conformation of chromatin and the nearly normal expression levels of HR genes in the mutant, this result suggests that chromatin is a major factor restricting HR in plants.
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