Evidence map›Paper›PMID 16980456›Full record

ArticleJournal of bacteriology2006

Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.

Rekha Seshadri, Sam W Joseph, Ashok K Chopra, Jian Sha, Jonathan Shaw, Joerg Graf, Daniel Haft, Martin Wu, Qinghu Ren, M J Rosovitz and 9 more

Abstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

153 citing papers in PubMed, 374 citations in OpenAlex.

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  7. Genomic signatures of resistance and adaptability in Aeromonas and Pseudomonas from a Brazilian Hope Spot.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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  9. Genomic Insights into the Pathogenicity of HypervirulentPathogens (Basel, Switzerland) · 2025
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  10. Microorganisms · 2025
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  11. eLife · 2025
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  14. Taxonomic classification of genusFujita medical journal · 2024
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  15. Tad pili contribute to the virulence and biofilm formation of virulentFrontiers in cellular and infection microbiology · 2024
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  19. Hiding in Plain Sight: Characterization ofAntibiotics (Basel, Switzerland) · 2023
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93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 2 countries.

Rekha SeshadriThe Institute for Genomic Research, Division of J. Craig Venter Institute, Rockville, MD 20850,USA. rseshadri@venterinstitute.org
Sam W Joseph
Ashok K Chopra
Jian Sha
Jonathan Shaw
Joerg Graf
Daniel Haft
Martin Wu
Qinghu Ren
M J Rosovitz
Ramana Madupu
Luke Tallon
Mary Kim
Shaohua Jin
Hue Vuong
O Colin Stine
Afsar Ali
Amy J Horneman
John F Heidelberg
J. Craig Venter Institute · USUniversity of Maryland, Baltimore · USThe University of Texas Medical Branch at Galveston · USUniversity of Connecticut · USUniversity of Maryland, College Park · USUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complete genome of Aeromonas hydrophila ATCC 7966(T) was sequenced. Aeromonas, a ubiquitous waterborne bacterium, has been placed by the Environmental Protection Agency on the Contaminant Candidate List because of its potential to cause human disease. The 4.7-Mb genome of this emerging pathogen shows a physiologically adroit organism with broad metabolic capabilities and considerable virulence potential. A large array of virulence genes, including some identified in clinical isolates of Aeromonas spp. or Vibrio spp., may confer upon this organism the ability to infect a wide range of hosts. However, two recognized virulence markers, a type III secretion system and a lateral flagellum, that are reported in other A. hydrophila strains are not identified in the sequenced isolate, ATCC 7966(T). Given the ubiquity and free-living lifestyle of this organism, there is relatively little evidence of fluidity in terms of mobile elements in the genome of this particular strain. Notable aspects of the metabolic repertoire of A. hydrophila include dissimilatory sulfate reduction and resistance mechanisms (such as thiopurine reductase, arsenate reductase, and phosphonate degradation enzymes) against toxic compounds encountered in polluted waters. These enzymes may have bioremediative as well as industrial potential. Thus, the A. hydrophila genome sequence provides valuable insights into its ability to flourish in both aquatic and host environments.

Indexed as

Genome, BacterialAeromonas hydrophilaArsenatesBacterial ProteinsCarrier ProteinsFimbriae, BacterialHumansMolecular Sequence DataOxidoreductasesPhylogenyPyrazolesSulfatesVirulenceVirulence FactorsArsenatesarsenic acidBacterial ProteinsCarrier ProteinsOxidoreductasesPyrazolesSulfatesthiopyrineVirulence Factors

Identifiers

PMID16980456
PMCPMC1698176
OpenAlexW2099473509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.