ArticleJournal of bacteriology2006
pH-dependent activation of the BarA-UvrY two-component system in Escherichia coli.
Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Optimizing experimental conditions: the role of buffered environments in microbial isolation, physiological studies, and taxonomic characterization.Applied and environmental microbiology · 2025Review
- Review
- Physiological and Transcriptomic Analyses ofMicroorganisms · 2023Article
- A Novel Role of the Two-Component System Response Regulator UvrY in EnterohemorrhagicInternational journal of molecular sciences · 2023Article
- Identification of Z nucleotides as an ancient signal for two-component system activation in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Comparative Genomics and Evolutionary Analysis of RNA-Binding Proteins of the CsrA Family in the GenusFrontiers in molecular biosciences · 2020Article
- Vibrio cholerae CsrA Directly RegulatesmBio · 2019Article
- An Extract Produced byFrontiers in microbiology · 2019Article
- Article
- Enhanced Fluorescent Siderophore Biosynthesis and Loss of Phenazine-1-Carboxamide in Phenotypic Variant ofFrontiers in microbiology · 2018Article
- Integrative FourD omics approach profiles the target network of the carbon storage regulatory system.Nucleic acids research · 2017Article
- Article
- The Mechanisms of Virulence Regulation by Small Noncoding RNAs in Low GC Gram-Positive Pathogens.International journal of molecular sciences · 2015Review
- Effects of the global regulator CsrA on the BarA/UvrY two-component signaling system.Journal of bacteriology · 2015Article
- CsrA impacts survival of Yersinia enterocolitica by affecting a myriad of physiological activities.BMC microbiology · 2015Article
- A direct link between the global regulator PhoP and the Csr regulon in Y. pseudotuberculosis through the small regulatory RNA CsrC.RNA biology · 2014Article
- The physiological stimulus for the BarA sensor kinase.Journal of bacteriology · 2010Article
- Complex regulatory network encompassing the Csr, c-di-GMP and motility systems of Salmonella Typhimurium.Environmental microbiology · 2010Article
- Signals, regulatory networks, and materials that build and break bacterial biofilms.Microbiology and molecular biology reviews : MMBR · 2009Article
- The RNA binding protein CsrA controls cyclic di-GMP metabolism by directly regulating the expression of GGDEF proteins.Molecular microbiology · 2008Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
The barA and uvrY genes of Escherichia coli encode a two-component sensor kinase and a response regulator, respectively. Although this system plays a major role in the regulation of central carbon metabolism, motility, and biofilm formation by controlling the expression of the CsrB and CsrC noncoding RNAs, the environmental conditions and the physiological signal(s) to which it responds remain obscure. In this study, we explored the effect of external pH on the activity of BarA/UvrY. Our results indicate that a pH lower than 5.5 provides an environment that does not allow activation of the BarA/UvrY signaling pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.