ArticleGenetics2006
Estimating recombination rates from single-nucleotide polymorphisms using summary statistics.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- The Bacterial Sequential Markov Coalescent.Genetics · 2017Article
- Impermanence of bacterial clones.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Unraveling recombination rate evolution using ancestral recombination maps.BioEssays : news and reviews in molecular, cellular and developmental biology · 2014Review
- Estimating population divergence time and phylogeny from single-nucleotide polymorphisms data with outgroup ascertainment bias.Molecular ecology · 2012Article
- An autosomal analysis gives no genetic evidence for complex speciation of humans and chimpanzees.Molecular biology and evolution · 2012Article
- Article
- Recombination yet inefficient selection along the Drosophila melanogaster subgroup's fourth chromosome.Molecular biology and evolution · 2010Article
- Contrasting methods of quantifying fine structure of human recombination.Annual review of genomics and human genetics · 2010Review
- Joint estimation of gene conversion rates and mean conversion tract lengths from population SNP data.Bioinformatics (Oxford, England) · 2009Article
- Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths.PLoS genetics · 2009Article
- Complex signatures of locus-specific selective pressures and gene conversion on Human Growth Hormone/Chorionic Somatomammotropin genes.Human mutation · 2008Article
- Exploring population genetic models with recombination using efficient forward-time simulations.Genetics · 2008Article
- Fraction of informative recombinations: a heuristic approach to analyze recombination rates.Genetics · 2008Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We describe a novel method for jointly estimating crossing-over and gene-conversion rates from population genetic data using summary statistics. The performance of our method was tested on simulated data sets and compared with the composite-likelihood method of R. R. Hudson. For several realistic parameter values, the new method performed similarly to the composite-likelihood approach for estimating crossing-over rates and better when estimating gene-conversion rates. We used our method to analyze a human data set recently genotyped by Perlegen Sciences.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.