Evidence map›Paper›PMID 16979747›Full record

ArticleUrology2006

Dysuria at onset of interstitial cystitis/painful bladder syndrome in women.

John W Warren, Christina Diggs, Vivian Brown, Walter A Meyer, Suzanne Markowitz, Patty Greenberg

Open access · greenAbstract read
In one paragraph

Article in Urology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John W WarrenDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. jwarren@medicine.umaryland.edu
Christina Diggs
Vivian Brown
Walter A Meyer
Suzanne Markowitz
Patty Greenberg
University of Maryland, Baltimore · US

Funding

A Case Control Study of Interstitial CystitisR01DK064880 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI WARREN, JOHN W · 2003 to 2006
$2.5M
NIDDK NIH HHS DK 064880NIDDK NIH HHS R01 DK064880
6 · The paper itself

Abstract

objectivesIn an ongoing national study of women to identify risk factors for interstitial cystitis/painful bladder syndrome (IC/PBS), dysuria was identified at the onset of IC/PBS in a small majority and the evidence for urinary tract infection was evaluated.

methodsIn women with IC/PBS of 12 months' duration or less, symptoms and pertinent laboratory tests at onset were assessed by telephone interview and medical record review.

resultsOf 138 women, 75 (54%) reported that they had started to experience burning or pain on urination at the onset of IC/PBS. Of those with urine cultures, 12 (34%) of 35 women with dysuria versus 1 (5%) of 21 without dysuria yielded a uropathogen (P = 0.01). Similarly, the microscopic white blood cell count and dipstick nitrites and leukocyte esterase were each significantly more common in the urine samples of those with dysuria than in those without. Additionally, 7 of 75 of those with dysuria versus 1 of 62 without dysuria reported chills or fever at the onset of IC/PBS. Using various definitions, the prevalence of urinary tract infection at the onset of IC/PBS, at a minimum, was 16% to 33% of those with dysuria versus less than 2% of those without dysuria (P < or = 0.003).

conclusionsA slight majority of women with IC/PBS reported dysuria at onset of their IC/PBS symptoms. The available laboratory data have suggested that dysuria may be a sensitive indicator of urinary tract infection at the onset of IC/PBS; however, its specificity is as yet undetermined.

Indexed as

AdultCystitis, InterstitialFemaleHumansPainSyndromeUrinary Bladder DiseasesUrinary Tract InfectionsUrination Disorders

Identifiers

PMID16979747
PMCPMC1626809
OpenAlexW1981135735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.