ArticleNucleic acids research2006
Identification of a plastid response element that acts as an enhancer within the Chlamydomonas HSP70A promoter.
Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 82 citations in OpenAlex.
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- Reproductive tissues-specific meta-QTLs and candidate genes for development of heat-tolerant rice cultivars.Plant molecular biology · 2020Article
- Genome-wide identification and characterization of Hsp70 gene family in Nicotiana tabacum.Molecular biology reports · 2019Article
- TaBT1, affecting starch synthesis and thousand kernel weight, underwent strong selection during wheat improvement.Journal of experimental botany · 2019Article
- Chloroplast Signaling Gates Thermotolerance in Arabidopsis.Cell reports · 2018Article
- Identification and Characterization of an Isoform Antifreeze Protein from the Antarctic Marine Diatom, Chaetoceros neogracile and Suggestion of the Core Region.Marine drugs · 2017Article
- Rye (Secale cereale) supernumerary (B) chromosomes associated with heat tolerance during early stages of male sporogenesis.Annals of botany · 2017Article
- Functional Characterization of a Missing Branch Component inFrontiers in plant science · 2017Article
- Prevalence, evolution, and cis-regulation of diel transcription in Chlamydomonas reinhardtii.G3 (Bethesda, Md.) · 2014Article
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- Heat shock factor 1 counteracts epigenetic silencing of nuclear transgenes in Chlamydomonas reinhardtii.Nucleic acids research · 2013Article
- Coordination of plastid and light signaling pathways upon development of Arabidopsis leaves under various photoperiods.Molecular plant · 2012Review
- Retrograde signaling from functionally heterogeneous plastids.Frontiers in plant science · 2012Article
- Transcription factor-dependent chromatin remodeling at heat shock and copper-responsive promoters in Chlamydomonas reinhardtii.The Plant cell · 2011Article
- Hemin and magnesium-protoporphyrin IX induce global changes in gene expression in Chlamydomonas reinhardtii.Plant physiology · 2011Article
- A soluble guanylate cyclase mediates negative signaling by ammonium on expression of nitrate reductase in Chlamydomonas.The Plant cell · 2010Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chloroplast-derived signals control a subset of nuclear genes in higher plants and eukaryotic algae. Among the types of signals identified are intermediates of chlorophyll biosynthesis such as Mg-protoporphyrin IX (MgProto). In Chlamydomonas reinhardtii, it was suggested that this tetrapyrrole mediates the light induction of chaperone gene HSP70A. Here we have analyzed cis elements involved in the regulation of HSP70A by MgProto and light. We identified two promoters and between their transcription start sites two regulatory regions that each may confer inducibility by MgProto and light to both HSP70A promoters. These regulatory regions, when cloned in front of basal non-light inducible heterologous promoters, conferred inducibility by MgProto and light. The orientation and distance independent function of these cis-regulatory sequences qualifies them as enhancers that mediate the response of nuclear genes to a chloroplast signal. Mutational analysis of one of these regulatory regions and an alignment with promoters of other MgProto-inducible genes revealed the sequence motif (G/C)CGA(C/T)N(A/G)N15 (T/C/A)(A/T/G) which, as shown for HSP70A, may confer MgProto responsiveness. This cis-acting sequence element is employed for induction of HSP70A by both MgProto and light, lending support to the model that light induction of this gene is mediated via MgProto.
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