ArticleJournal of virology2006
Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products.
Article in Journal of virology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 124 citations in OpenAlex.
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- Ultrastructural and transcriptional changes during a giant virus infection of a green alga.Npj viruses · 2025Article
- Acanthamoeba polyphaga de novo transcriptome and its dynamics during Mimivirus infection.Scientific reports · 2024Article
- Review
- Amoebal Tubulin Cleavage Late during Infection Is a Characteristic Feature ofMicrobiology spectrum · 2022Article
- Giant virus biology and diversity in the era of genome-resolved metagenomics.Nature reviews. Microbiology · 2022Review
- The Astounding World of Glycans from Giant Viruses.Chemical reviews · 2022Review
- Megaviruses contain various genes encoding for eukaryotic vesicle trafficking factors.Traffic (Copenhagen, Denmark) · 2022Article
- Giant viruses of themicroLife · 2022Article
- Expanding the Occurrence of Polysaccharides to the Viral World: The Case of Mimivirus.Angewandte Chemie (International ed. in English) · 2021Article
- Proteomics and Lipidomics Investigations to Decipher the Behavior ofMicroorganisms · 2020Article
- Yaravirus: A novel 80-nm virus infectingProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Evolution of a major virion protein of the giant pandoraviruses from an inactivated bacterial glycoside hydrolase.Virus evolution · 2020Article
- Structural and Proteomic Studies of theFrontiers in microbiology · 2020Article
- Virophages of Giant Viruses: An Update at Eleven.Viruses · 2019Review
- Mimivirus encodes a multifunctional primase with DNA/RNA polymerase, terminal transferase and translesion synthesis activities.Nucleic acids research · 2019Article
- Complex Membrane Remodeling during Virion Assembly of the 30,000-Year-Old Mollivirus Sibericum.Journal of virology · 2019Article
- On the occurrence of cytochrome P450 in viruses.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Kinetics of Mimivirus Infection Stages Quantified Using Image Flow Cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2019Article
- Guarani Virophage, a New Sputnik-Like Isolate From a Brazilian Lake.Frontiers in microbiology · 2019Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acanthamoeba polyphaga mimivirus is the largest known virus in both particle size and genome complexity. Its 1.2-Mb genome encodes 911 proteins, among which only 298 have predicted functions. The composition of purified isolated virions was analyzed by using a combined electrophoresis/mass spectrometry approach allowing the identification of 114 proteins. Besides the expected major structural components, the viral particle packages 12 proteins unambiguously associated with transcriptional machinery, 3 proteins associated with DNA repair, and 2 topoisomerases. Other main functional categories represented in the virion include oxidative pathways and protein modification. More than half of the identified virion-associated proteins correspond to anonymous genes of unknown function, including 45 "ORFans." As demonstrated by both Western blotting and immunogold staining, some of these "ORFans," which lack any convincing similarity in the sequence databases, are endowed with antigenic properties. Thus, anonymous and unique genes constituting the majority of the mimivirus gene complement encode bona fide proteins that are likely to participate in well-integrated processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.