ReviewEuropean journal of epidemiology2006
Conditions in utero and cancer risk.
Review in European journal of epidemiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Second-To-Fourth Digit Ratio (2D:4D) in Breast Cancer: A Systematic Review.American journal of human biology : the official journal of the Human Biology Council · 2026Pooled it
- The Association of Digit Ratio (2D : 4D) with Cancer: A Systematic Review and Meta-Analysis.Disease markers · 2018Pooled it
- Testicular cancer in twins: a meta-analysis.British journal of cancer · 2008Pooled it
- Intrauterine environments and breast cancer risk: meta-analysis and systematic review.Breast cancer research : BCR · 2008Pooled it
- Bibliometric analysis of reviews of outcomes for adults with a complex perinatal history.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Digit ratio (2D:4D), laryngeal cancer and vocal fold leukoplakia.Journal of cancer research and clinical oncology · 2023Article
- In Utero Programming of Testicular Cancer.Journal of developmental biology · 2021Review
- In Utero Exposure to Bisphenol a Promotes Mammary Tumor Risk in MMTV-Erbb2 Transgenic Mice Through the Induction of ER-erbB2 Crosstalk.International journal of molecular sciences · 2020Article
- The Relationship of Pre and Early Postnatal Risk Factors with Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Risk of Sex-Specific Cancers in Opposite-Sex and Same-Sex Twins in Denmark and Sweden.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015Article
- Racial variation in umbilical cord blood leptin concentration in male babies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2011Article
- Birth length and weight as predictors of breast cancer prognosis.BMC cancer · 2010Article
- Etiology of testicular germ cell tumors: lumping or splitting? A plea against lumping.European journal of epidemiology · 2009Article
- Characteristics related to the maternal intrauterine environment and risk of epithelial ovarian cancer.Annals of epidemiology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is increasing recognition that conditions in utero are of importance for later cancer risk in several organs, particularly the testis and breast. A review of the most recent literature on this topic is therefore warranted. The PubMed database was searched for relevant recent literature on intrauterine conditions associated with cancer risk later in life, with particular emphasis on the testis, breast, but also studies pertaining to other organs were included. Epidemiological and experimental data support the hypothesis that factors acting in utero play a role in the development of cancer in the testis and breast. For other organs, such as the prostate, urinary system and colorectum, the results are inconclusive. While conditions during foetal life are associated with later cancer risk in the testis and breast, the biological mechanisms are for the most part elusive. They are, however, likely to involve hormonal disturbances, number of cells at risk, and genetic or epigenetic events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.