ArticleCell cycle (Georgetown, Tex.)2006
Condensin function in mitotic nucleolar segregation is regulated by rDNA transcription.
Article in Cell cycle (Georgetown, Tex.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
32 citing papers in PubMed, 45 citations in OpenAlex.
- Phenotypic tolerance for rDNA copy number variation within the natural range of C. elegans.PLoS genetics · 2025Article
- A Yeast Mitotic Tale for the Nucleus and the Vacuoles to Embrace.International journal of molecular sciences · 2023Review
- Nucleolar Organizer Regions as Transcription-Based Scaffolds of Nucleolar Structure and Function.Results and problems in cell differentiation · 2022Article
- The Multiple Roles of the Cdc14 Phosphatase in Cell Cycle Control.International journal of molecular sciences · 2020Review
- Condensin locates at transcriptional termination sites in mitosis, possibly releasing mitotic transcripts.Open biology · 2019Article
- Review
- Condensin action and compaction.Current genetics · 2019Review
- A novel TPR-BEN domain interaction mediates PICH-BEND3 association.Nucleic acids research · 2017Article
- Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood.American journal of human genetics · 2017Article
- Temperature-dependent regulation of rDNA condensation in Saccharomyces cerevisiae.Cell cycle (Georgetown, Tex.) · 2017Article
- The Epigenetic Pathways to Ribosomal DNA Silencing.Microbiology and molecular biology reviews : MMBR · 2016Review
- Levels of Ycg1 Limit Condensin Function during the Cell Cycle.PLoS genetics · 2016Article
- Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation.Nature communications · 2015Article
- Nur1 dephosphorylation confers positive feedback to mitotic exit phosphatase activation in budding yeast.PLoS genetics · 2015Article
- Condensin aids sister chromatid decatenation by topoisomerase II.Nucleic acids research · 2014Article
- Article
- Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription.Nature cell biology · 2011Article
- Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast.Cellular and molecular life sciences : CMLS · 2011Review
- One-hit wonders of genomic instability.Cell division · 2010Article
- Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation.PloS one · 2009Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Chromosome condensation is established and maintained by the condensin complex. The mechanisms governing loading of condensin onto specific chromosomal sites remain unknown. To elucidate the molecular pathways that determine condensin binding to the nucleolar organizer, a key condensin binding site, we analyzed the properties of condensin-bound sites within the rDNA repeat in budding yeast and demonstrated that the bulk of mitotic condensin binding to rDNA is reduced or eliminated when Pol I transcription is elevated. Conversely, when Pol I transcription is repressed either by rapamycin treatment or by promoter shut-off, condensin binding to rDNA is increased. This novel potential role for constitutive and/or periodic repression of Pol I transcription in rDNA condensin loading is an important factor in determining the segregation proficiency of NOR-containing chromosomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.