Evidence map›Paper›PMID 16967973›Full record

ArticleJournal of the American Chemical Society2006

Stereochemical and regiochemical trends in the selective detection of saccharides.

Shan Jiang, Jorge O Escobedo, Kyu Kwang Kim, Onur Alptürk, George K Samoei, Sayo O Fakayode, Isiah M Warner, Oleksandr Rusin, Robert M Strongin

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Progress toward red and near-infrared (NIR) emitting saccharide sensors.Pure and applied chemistry. Chimie pure et appliquee · 2012
    Article
  5. Article
  6. Article
  7. Article
  8. Detecting specific saccharides via a single indicator.Chemical communications (Cambridge, England) · 2011
    Article
  9. Article
  10. Differential sensing of sugars by colorimetric arrays.Current opinion in chemical biology · 2010
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shan JiangDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Jorge O Escobedo
Kyu Kwang Kim
Onur Alptürk
George K Samoei
Sayo O Fakayode
Isiah M Warner
Oleksandr Rusin
Robert M Strongin

Funding

Synthesis and Study of Novel Sensing AgentsR01EB002044 · NIBIB · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2003 to 2010
$1.6M
A Simple and Robust Indicator for GlutathioneR15EB016870 · NIBIB · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2014 to 2014
$435k
NIBIB NIH HHS R01 EB002044NIBIB NIH HHS R15 EB016870
6 · The paper itself

Abstract

Several discreet sugar-boronate complexes exist in solution. This is due to the complex equilibria between isomeric species of even the simplest monosaccharides. In the current investigation, we determine the regio- and stereochemical features of the various equilibrating sugar isomers that induce signal transduction in boronic acid chemosensors such as 1 as well as 2 and 3. We present a unique example of a chemosensor (1) that is selective for ribose, adenosine, nucleotides, nucleosides, and congeners. As a result of this study, we are able to predict and achieve selective fluorescence and colorimetric responses to specific disaccharides as a consequence of their terminal sugar residue linkage patterns and configurations. We also find that the combined use of chemosensors exhibiting complementary reactivities may be used cooperatively to obtain enhanced selectivity for ribose and rare saccharides.

Indexed as

AdenosineBoronic AcidsCarbohydrate ConformationColorimetryFructoseGlucoseModels, MolecularMonosaccharidesNuclear Magnetic Resonance, BiomolecularNucleosidesNucleotidesOligosaccharidesRiboseSpectrophotometry, UltravioletStereoisomerismAdenosinealloseBoronic AcidsFructoseGlucoseMonosaccharidesNucleosidesNucleotidesOligosaccharidespsicoseRibose

Identifiers

PMID16967973
PMCPMC2662350

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.