Evidence map›Paper›PMID 16967300›Full record

ArticleEuropean journal of clinical pharmacology2006

Effect of intervention promoting a reduction in antibiotic prescribing by improvement of diagnostic procedures: a prospective, before and after study in general practice.

Lars Bjerrum, Josep M Cots, Carl Llor, Núria Molist, Anders Munck

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Article in European journal of clinical pharmacology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Estimating cost savings from reducing antibiotic overprescription in european general practices.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
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  9. Effectiveness of physician-targeted interventions to improve antibiotic use for respiratory tract infections.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
    Review
  10. Antibiotic resistance amongst healthcare-associated pathogens in China.International journal of antimicrobial agents · 2012
    Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lars BjerrumResearch Unit for General Practice, University of Southern Denmark, J. B. Winsløws Vej 9 A, DK-5000, Odense C, Denmark. lbjerrum@health.sdu.dk
Josep M Cots
Carl Llor
Núria Molist
Anders Munck

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate if an intervention aimed at improving the quality of the diagnostic procedures in Spanish general practice could lower antibiotic prescribing in patients with respiratory tract infections (RTIs).

methodsGPs in the intervention group (n=17) registered all patients with RTIs during a 3-week period before and after the intervention. The intervention was aimed at reducing prescribing of inappropriate antibiotics for RTIs by improving the diagnostic procedures and thereby helping the GPs to distinguish between bacterial and viral infections. It consisted of courses in management of RTI according to local clinical guidelines, and included implementation of two rapid diagnostic tests (StrepA and CRP measurement). Diagnoses and prescribing of antibiotics were assessed before and after the intervention, and compared to a control group not exposed to intervention (35 GPs).

resultsThe intervention led to a significant reduction in antibiotic prescribing. Before the intervention 36% (29%-44%) of consultations were followed by antibiotic prescribing, after the intervention 24% (20%-29%). Antibiotic prescribing in the control group not exposed to intervention was 32% (27%-38%). The reduction was most pronounced in patients with sinusitis and lower RTIs.

conclusionQuality improvement of diagnostic procedures may lead to a reduction of antibiotic prescribing in primary health care in Spain.

Indexed as

Practice Patterns, Physicians'AdultAnti-Bacterial AgentsBacterial InfectionsDiagnosis, DifferentialDrug PrescriptionsDrug Resistance, BacterialDrug Utilization ReviewFemaleHumansMaleMicrobiological TechniquesMiddle AgedPhysicians, FamilyProspective StudiesRespiratory Tract InfectionsAnti-Bacterial Agents

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.