Evidence map›Paper›PMID 16967283›Full record

ArticlePediatric nephrology (Berlin, Germany)2007

Prognostic significance of microalbuminuria in postdiarrheal hemolytic uremic syndrome.

Randall Lou-Meda, Robert S Oakes, Jarom N Gilstrap, Christopher G Williams, Richard L Siegler

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. HUS and TTP in Children.Pediatric clinics of North America · 2013
    Review
  5. Proteinuria and progression of glomerular diseases.Pediatric nephrology (Berlin, Germany) · 2013
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Randall Lou-MedaDivision of Nephrology and Hypertension, Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, UT, USA.
Robert S Oakes
Jarom N Gilstrap
Christopher G Williams
Richard L Siegler
University of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients who survive the acute phase of postdiarrheal hemolytic uremic syndrome (D+ HUS) may develop renal complications after years of apparent recovery. The optimal regimen for monitoring these children is unclear. We therefore determined if screening for microalbuminuria, in the absence of overt proteinuria at follow-up, increased the sensitivity for predicting long-term renal-related sequelae. We found that screening for microalbuminurea, within the first 6-18 months following an episode of HUS, increased the sensitivity for predicting later sequelae from 22 to 66.7%, compared to screening for overt proteinuria alone. These findings, if confirmed by a larger cohort with more years of follow-up, may facilitate early initiation of intervention strategies designed to reduce progressive renal damage.

Indexed as

AdolescentAlbuminuriaChildChild, PreschoolDiarrheaDisease ProgressionGlomerular Filtration RateHemolytic-Uremic SyndromeHumansHypertensionInfantKidney DiseasesPredictive Value of TestsPrognosisProteinuriaRetrospective Studies

Identifiers

PMID16967283
OpenAlexW1992776772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.