Adverse events in clinical trials with azathioprine and mesalamine for prevention of postoperative recurrence of Crohn's disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

25 citing papers in PubMed, 9 syntheses or guidelines pooled it, 59 citations in OpenAlex.

1. Maximizing the diagnostic information from biopsies in chronic inflammatory bowel diseases: recommendations from the Erlangen International Consensus Conference on Inflammatory Bowel Diseases and presentation of the IBD-DCA score as a proposal for a new index for histologic activity assessment in ulcerative colitis and Crohn's disease.Virchows Archiv : an international journal of pathology · 2021
   Guideline
2. Pancreatitis associated with azathioprine and 6-mercaptopurine use in Crohn's disease: a systematic review.Frontline gastroenterology · 2021
   Pooled it
3. Interventions for maintenance of surgically induced remission in Crohn's disease: a network meta-analysis.The Cochrane database of systematic reviews · 2019
   Pooled it
4. Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease.The Cochrane database of systematic reviews · 2019
   Pooled it
5. Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease.The Cochrane database of systematic reviews · 2019
   Pooled it
6. ACG Clinical Guideline: Management of Crohn's Disease in Adults.The American journal of gastroenterology · 2018
   Guideline
7. Comparative efficacy of pharmacologic interventions in preventing relapse of Crohn's disease after surgery: a systematic review and network meta-analysis.Gastroenterology · 2015
   Pooled it
8. Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease.The Cochrane database of systematic reviews · 2014
   Pooled it
9. Interventions for prevention of post-operative recurrence of Crohn's disease.The Cochrane database of systematic reviews · 2009
   Pooled it
10. Early diagnosis and treatment of postoperative endoscopic recurrence of Crohn's disease: partial benefit by infliximab--a pilot study.Digestive diseases and sciences · 2012
    Trial
11. Post-operative prevention and monitoring of Crohn's disease recurrence.Gastroenterology report · 2022
    Review
12. Pharmacological Prevention of Postoperative Recurrence in Crohn's Disease.Drugs · 2020
    Review
13. Pharmacological Prevention and Management of Postoperative Relapse in Pediatric Crohn's Disease.Paediatric drugs · 2019
    Review
14. Perioperative use of immunosuppressive medications in patients with Crohn's disease in the new "biological era".Gastroenterology report · 2017
    Article
15. Surgical Considerations in the Treatment of Small Bowel Crohn's Disease.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Review
16. Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective.World journal of gastroenterology · 2016
    Review
17. Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review.Medicine · 2016
    Article
18. A Practical Approach to Preventing Postoperative Recurrence in Crohn's Disease.Current gastroenterology reports · 2016
    Review
19. Use of Methotrexate in the Treatment of Inflammatory Bowel Diseases.Inflammatory bowel diseases · 2016
    Review
20. Postoperative Effects of Thiopurines in Patients with Intestinal Behçet's Disease.Digestive diseases and sciences · 2015
    Article

Corrections and comments

• Comment on
  Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis.2006
• Comment on
  Immunosuppressive drugs in ulcerative colitis: twisting facts to suit theories?2006

Authors and funding

8 authors at 4 institutions in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as