Evidence map›Paper›PMID 16966437›Full record

ReviewVeterinary pathology2006

Collectins and cationic antimicrobial peptides of the respiratory epithelia.

B Grubor, D K Meyerholz, M R Ackermann

Open access · greenAbstract readReview
In one paragraph

Review in Veterinary pathology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 69 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Single-cell Raman spectroscopy identifiesFrontiers in microbiology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Ontogeny of the immune response in the ovine lung.Immunological investigations · 2012
    Article
  19. The potential of antimicrobial peptides as biocides.International journal of molecular sciences · 2011
    Review
  20. Innate immunology of bovine respiratory disease.The Veterinary clinics of North America. Food animal practice · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B GruborDepartment of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. branka.grubor@bms.com
D K Meyerholz
M R Ackermann
Iowa State University · US

Funding

Preterm birth, lung innate immunity, and RSVR01AI062787 · NIAID · IOWA STATE UNIVERSITY · PI ACKERMANN, MARK R · 2005 to 2009
$2.0M
VEGF regulation of surfactant proteins in preventing RSVK08AI055499 · NIAID · IOWA STATE UNIVERSITY · PI MEYERHOLZ, DAVID K · 2003 to 2005
$337k
NIAID NIH HHS 5K08 AI 055499-03NIAID NIH HHS 5R01 AI 062787-02NIAID NIH HHS K08 AI055499NIAID NIH HHS R01 AI062787
6 · The paper itself

Abstract

The respiratory epithelium is a primary site for the deposition of microorganisms that are acquired during inspiration. The innate immune system of the respiratory tract eliminates many of these potentially harmful agents preventing their colonization. Collectins and cationic antimicrobial peptides are antimicrobial components of the pulmonary innate immune system produced by respiratory epithelia, which have integral roles in host defense and inflammation in the lung. Synthesis and secretion of these molecules are regulated by the developmental stage, hormones, as well as many growth and immunoregulatory factors. The purpose of this review is to discuss antimicrobial innate immune elements within the respiratory tract of healthy and pneumonic lung with emphasis on hydrophilic surfactant proteins and beta-defensins.

Indexed as

AnimalsAntimicrobial Cationic PeptidesCollectinsRespiratory MucosaAntimicrobial Cationic PeptidesCollectins

Identifiers

PMID16966437
PMCPMC2786072
OpenAlexW2140425562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.