ReviewEnvironmental health perspectives2006
Trichloroethylene cancer epidemiology: a consideration of select issues.
Review in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- The epidemiology of cancer among police officers.American journal of industrial medicine · 2013Pooled it
- Trichloroethylene and cancer: systematic and quantitative review of epidemiologic evidence for identifying hazards.International journal of environmental research and public health · 2011Pooled it
- A meta-analysis of occupational trichloroethylene exposure and liver cancer.International archives of occupational and environmental health · 2007Pooled it
- Occupational exposures and cancer risk in commercial laundry and dry cleaning industries: a scoping review.BMC public health · 2023Article
- Article
- The global, regional, and national burden of kidney cancer and attributable risk factor analysis from 1990 to 2017.Experimental hematology & oncology · 2020Article
- Prognostic biomarkers in renal cell carcinoma: is there a relationship with obesity?Translational andrology and urology · 2019Review
- Incidence and mortality of kidney cancer: temporal patterns and global trends in 39 countries.Scientific reports · 2017Article
- Imaging and Screening of Kidney Cancer.Radiologic clinics of North America · 2017Review
- Non‑infective occupational risk factors for hepatocellular carcinoma: A review (Review).Molecular medicine reports · 2017Review
- Comparison of hematological alterations and markers of B-cell activation in workers exposed to benzene, formaldehyde and trichloroethylene.Carcinogenesis · 2016Article
- Historical occupational trichloroethylene air concentrations based on inspection measurements from Shanghai, China.The Annals of occupational hygiene · 2015Article
- Human health effects of trichloroethylene: key findings and scientific issues.Environmental health perspectives · 2013Review
- The epidemiology and risk factors for renal cancer.Current urology · 2013Review
- Risk of hepatocellular carcinoma in workers exposed to chemicals.Hepatitis monthly · 2012Article
- Concentration of trichloroethylene in breast milk and household water from Nogales, Arizona.Environmental science & technology · 2012Article
- Using bioinformatic approaches to identify pathways targeted by human leukemogens.International journal of environmental research and public health · 2012Article
- Current understanding of lifestyle and environmental factors and risk of non-hodgkin lymphoma: an epidemiological update.Journal of cancer epidemiology · 2012Article
- Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis.Critical reviews in toxicology · 2011Article
- Insights from epidemiology into dichloromethane and cancer risk.International journal of environmental research and public health · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A large body of epidemiologic evidence exists for exploring causal associations between cancer and trichloroethylene (TCE) exposure. The U.S. Environmental Protection Agency 2001 draft TCE health risk assessment concluded that epidemiologic studies, on the whole, support associations between TCE exposure and excess risk of kidney cancer, liver cancer, and lymphomas, and, to a lesser extent, cervical cancer and prostate cancer. As part of a mini-monograph on key issues in the health risk assessment of TCE, this article reviews recently published scientific literature examining cancer and TCE exposure and identifies four issues that are key to interpreting the larger body of epidemiologic evidence: a) relative sensitivity of cancer incidence and mortality data ; b) different classifications of lymphomas, including non-Hodgkin lymphoma ; c) differences in data and methods for assigning TCE exposure status ; and d) different methods employed for causal inferences, including statistical or meta-analysis approaches. The recent epidemiologic studies substantially expand the epidemiologic database, with seven new studies available on kidney cancer and somewhat fewer studies available that examine possible associations at other sites. Overall, recently published studies appear to provide further support for the kidney, liver, and lymphatic systems as targets of TCE toxicity, suggesting, as do previous studies, modestly elevated (typically 1.5-2.0) site-specific relative risks, given exposure conditions in these studies. However, a number of challenging issues need to be considered before drawing causal conclusions about TCE exposure and cancer from these data.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.