Evidence map›Paper›PMID 16965698›Full record

ArticleEmerging infectious diseases2006

Streptococcus suis sequence type 7 outbreak, Sichuan, China.

Changyun Ye, Xiaoping Zhu, Huaiqi Jing, Huamao Du, Mariela Segura, Han Zheng, Biao Kan, Lili Wang, Xuemei Bai, Yongyun Zhou and 21 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed.

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  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Changyun YeState Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Changping, Beijing 102206, People's Republic of China.
Xiaoping Zhu
Huaiqi Jing
Huamao Du
Mariela Segura
Han Zheng
Biao Kan
Lili Wang
Xuemei Bai
Yongyun Zhou
Zhigang Cui
Shouying Zhang
Dong Jin
Na Sun
Xia Luo
Ji Zhang
Zhaolong Gong
Xin Wang
Lei Wang
Hui Sun
Zhenjun Li
Qiangzheng Sun
Honglu Liu
Boqing Dong
Changwen Ke
Hui Yuan
Hua Wang
Kecheng Tian
Yu Wang
Marcelo Gottschalk
Jianguo Xu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An outbreak of Streptococcus suis serotype 2 emerged in the summer of 2005 in Sichuan Province, and sporadic infections occurred in 4 additional provinces of China. In total, 99 S. suis strains were isolated and analyzed in this study: 88 isolates from human patients and 11 from diseased pigs. We defined 98 of 99 isolates as pulse type I by using pulsed-field gel electrophoresis analysis of SmaI-digested chromosomal DNA. Furthermore, multilocus sequence typing classified 97 of 98 members of the pulse type I in the same sequence type (ST), ST-7. Isolates of ST-7 were more toxic to peripheral blood mononuclear cells than ST-1 strains. S. suis ST-7, the causative agent, was a single-locus variant of ST-1 with increased virulence. These findings strongly suggest that ST-7 is an emerging, highly virulent S. suis clone that caused the largest S. suis outbreak ever described.

Indexed as

Disease OutbreaksAnimalsChinaDNA, BacterialElectrophoresis, Gel, Pulsed-FieldHumansMolecular Sequence DataPhylogenyPolymerase Chain ReactionSequence Analysis, DNASerotypingStreptococcal InfectionsStreptococcus suisSwineSwine DiseasesVirulenceDNA, Bacterial

Identifiers

PMID16965698
PMCPMC3291228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.