ArticleILAR journal2006
Issues to consider for preparing ferrets as research subjects in the laboratory.
Article in ILAR journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Ferret as a model system for studying the anatomy and function of the prefrontal cortex: A systematic review.Neuroscience and biobehavioral reviews · 2024Pooled it
- Feeding and Husbandry Practices in Pet Ferrets (Mustela putorius furo): A Cross-Sectional International Study.Veterinary medicine and science · 2026Article
- Paired versus Single Housing of Ferrets (Mustela putorius furo) Does Not Influence Experimental Outcomes of Influenza A Virus Pathogenesis Studies.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Ferrets and genetically modified ferrets as model organisms in biomedical research: a review.Frontiers in genome editing · 2026Review
- Influence of volatile anaesthetics on haematology and clinical chemistry in ferrets.BMC veterinary research · 2024Article
- Behavioral assessment of well-being in the naïve laboratory ferret (Mustela putorius furo).Scientific reports · 2024Article
- Ferrets as Models for Viral Respiratory Disease.Comparative medicine · 2023Review
- Acute pancreatitis-induced islet dysfunction in ferrets.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2021Article
- Regen med therapeutic opportunities for fighting COVID-19.Stem cells translational medicine · 2021Article
- Assessment of naloxone as a therapeutic for inhaled carfentanil in the ferret.Toxicology reports · 2020Article
- Seasonal weight changes in laboratory ferrets.PloS one · 2020Article
- Spontaneous abdominal hemangiosarcoma in a ferret.Journal of toxicologic pathology · 2019Article
- Founder events, isolation, and inbreeding: Intercontinental genetic structure of the domestic ferret.Evolutionary applications · 2018Article
- Establishing the ferret as a gyrencephalic animal model of traumatic brain injury: Optimization of controlled cortical impact procedures.Journal of neuroscience methods · 2017Article
- Endocrinopathy and Aging in Ferrets.Veterinary pathology · 2016Review
- Is the ferret a suitable species for studying perinatal brain injury?International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2015Review
- Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets.PloS one · 2014Article
- Endogenous lentiviral elements in the weasel family (Mustelidae).Molecular biology and evolution · 2012Article
- Ferrets further disease research.Lab animal · 2012Article
- Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity--state of the art.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The domestic or European ferret (Mustela putorius furo) has been domesticated for thousands of years. Ferrets have been used for hunting and fur production, as pets, and as models in biomedical research. Despite the relatively small numbers used in the laboratory, ferrets have some unique applications including study of human influenza and severe acute respiratory syndrome (SARS)-associated corona virus. They have served as models for peptic ulcer disease, carotenoid metabolism, cystic fibrosis, and drug emesis screening, among others. Most research ferrets are males, due to estrus-related health problems in females. They may be housed conventionally and are easy to care for when their biology and behavior are understood. Due to the small number of ferret suppliers, animals are often shipped long distances, requiring air transport and intermediate handlers. It is important to minimize shipment stress, especially with weanling and pregnant animals. Additional expertise is required for success with pregnant and whelping ferrets and for rearing of neonates. The animals have specific dietary requirements, and proper nutrition is key. Successful housing requires knowledge of ferret behaviors including social behavior, eating habits, a general inquisitive nature, and a species-typical need to burrow and hide. Regular handling is necessary to maintain well-being. A ferret health care program consists of physical examination, immunization, clinical pathology, and a working knowledge of common ferret diseases. Various research methodologies have been described, from basic procedures such as blood collection to major invasive survival surgery. Ferrets have a distinct niche in biomedical research and are hardy animals that thrive well in the laboratory.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.