ArticleNucleic acids research2006
Organization of chromosome ends in the rice blast fungus, Magnaporthe oryzae.
Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- FoTeRs: a novel family of telomere-associated retrotransposons in Fusarium oxysporum.Mobile DNA · 2025Article
- Transposable elements create distinct genomic niches for effector evolution among Magnaporthe oryzae lineages.BMC biology · 2025Article
- An annotated near-complete sequence assembly of the Magnaporthe oryzae 70-15 reference genome.Scientific data · 2025Article
- Characterization and organization of telomeric-linked helicase (tlh) gene families in Fusarium oxysporum.Current genetics · 2024Article
- Near complete assembly of Pyricularia penniseti infecting Cenchrus grass identified its eight core chromosomes.Scientific data · 2024Article
- Complete genome of the Medicago anthracnose fungus,Microbial genomics · 2024Article
- First telomere-to-telomere gapless assembly of the rice blast fungus Pyricularia oryzae.Scientific data · 2024Article
- Article
- How to Completely Squeeze a Fungus-Advanced Genome Mining Tools for Novel Bioactive Substances.Pharmaceutics · 2022Review
- Virulence Pattern ofTropical life sciences research · 2021Article
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- Reference genome assembly for Australian Ascochyta lentis isolate Al4.G3 (Bethesda, Md.) · 2021Article
- Telomere Roles in Fungal Genome Evolution and Adaptation.Frontiers in genetics · 2021Article
- Sequence analysis of wheat subtelomeres reveals a high polymorphism among homoeologous chromosomes.The plant genome · 2020Article
- Transposon-mediated telomere destabilization: a driver of genome evolution in the blast fungus.Nucleic acids research · 2020Article
- Reference Genome Assembly for AustralianG3 (Bethesda, Md.) · 2020Article
- Novel Variation and Evolution ofFrontiers in genetics · 2020Article
- Analysis of Epichloë festucae small secreted proteins in the interaction with Lolium perenne.PloS one · 2019Article
- The Structure of a Conserved Telomeric Region Associated with Variant Antigen Loci in the Blood Parasite Trypanosoma congolense.Genome biology and evolution · 2018Article
- Phylogenetic classification and generic delineation ofStudies in mycology · 2018Article
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8 authors.
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Abstract
Eukaryotic pathogens of humans often evade the immune system by switching the expression of surface proteins encoded by subtelomeric gene families. To determine if plant pathogenic fungi use a similar mechanism to avoid host defenses, we sequenced the 14 chromosome ends of the rice blast pathogen, Magnaporthe oryzae. One telomere is directly joined to ribosomal RNA-encoding genes, at the end of the approximately 2 Mb rDNA array. Two are attached to chromosome-unique sequences, and the remainder adjoin a distinct subtelomere region, consisting of a telomere-linked RecQ-helicase (TLH) gene flanked by several blocks of tandem repeats. Unlike other microbes, M.oryzae exhibits very little gene amplification in the subtelomere regions-out of 261 predicted genes found within 100 kb of the telomeres, only four were present at more than one chromosome end. Therefore, it seems unlikely that M.oryzae uses switching mechanisms to evade host defenses. Instead, the M.oryzae telomeres have undergone frequent terminal truncation, and there is evidence of extensive ectopic recombination among transposons in these regions. We propose that the M.oryzae chromosome termini play more subtle roles in host adaptation by promoting the loss of terminally-positioned genes that tend to trigger host defenses.
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